Abstract:ObjectiveTo investigate the role of H+/K+ATPase in the proliferation of pepsin‐induced vocal cord leukoplakia (VCL) cells.Study DesignTranslation research.SettingAffiliated Hospital of University.MethodsImmunohistochemistry was used to detect pepsin, H+/K+ATPase (ATP4A and ATP4B subunits) in VCL cells with varying degrees of dysplasia. After primary cultures of VCL cells had been established, the effects of acidified pepsin on the proliferation, autophagy, and H+/K+‐ATPase distribution of VCL cells were invest… Show more
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