Penoscrotal Transposition: Review of 53 Patients

Abstract

We identified a subgroup of patients with a family history of penoscrotal transposition. Treatment requires an awareness of the association with other organ system anomalies. The Glenn-Anderson technique was the most successful method to correct transposition. Most patients required release of chordee and complex urethroplasty for hypospadias.

Benign penile skin anomalies in children: a primer for pediatricians

“…The largest series reported so far comprises 53 cases treated over a 25-year period at the Mayo Clinic. [63] The malformation is seldom isolated and is more commonly seen in patients with severe variants of hypospadias (80% in the series from the Mayo Clinic). Up to 100% of cases were found to have associated renal defects, and also musculoskeletal, gastrointestinal, cardiac, and central nervous system associated anomalies have been reported.…”

“…Of note, surgery for the correction of peno-scrotal transposition is fraught with a complication rate as high as 70%. [63] Focal lesions Penile/scrotal cysts Cysts can arise at any level in the penis or scrotum. They can be congenital or acquired.…”

Female counterpart of shawl scrotum in aarskog-scott syndrome

“…The etiology of penoscrotal transposition remains uncertain (2). Embryological origin of the penis and scrotum are respectively the genital tubercle and labioscrotal folds.…”

Extreme penoscrotal transposition

“…[1,2] Less than 20 cases of extreme degree of PST with normal scrotum have been reported in the literature. [1][2][3][4][5][6][7] PST results from abnormal genital tubercle development around the 6th week gestation. It is associated with delay in the midline fusion of the urethral folds.…”

“…Although the occurrence of most reported cases of PST has been sporadic, other congenital anomalies like hypospadias, chordee and renal agenesis or dysplasia could be found in approximately 90% of patients. [5] Gastrointestinal abnormalities, predominantly imperforate anus were found in 30% of cases. [8] PST may present with a broad spectrum of abnormalities ranging from simple shawl scrotum (doughnut scrotum) to very complex extreme transposition with cardiac, gastrointestinal, craniofacial, central nervous system, genital and urological malformations associated.…”