Abstract:Telah dilakukan kokristalisasi asam mefenamat (AM) dengan para-aminobenzoic acid (PABA) sebagai koformer dengan menggunakan metode liquid‐assisted grinding. Penelitian ini bertujuan untuk mengetahui apakah asam mefenamat dapat ditingkatkan laju disolusinya melalui pembentukan kokristal dengan PABA. Kokristal AM-PABA dibuat dengan perbandingan molar 1:2. Laju disolusi kokristal AM-PABA meningkat 1,45 kali lebih baik dibandingkan asam mefenamat murni. Hasil karakterisasi menunjukkan terbentuknya fase kristal bar… Show more
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