Pengaruh yogurt sinbiotik pisang terhadap kadar glukosa dan insulin tikus sindrom metabolik

Abstract

Background

Yogurt is Effective in Reduction of Fasting Blood Glucose Levels of Prediabetes in Employees

“…IGT blood glucose levels in respondents who were given yogurt in this study decreased / decreased (16%) than fasting blood glucose levels in respondents who were not given yogurt. The results of the study are consistent with the research which showed that there were significant differences in mean blood glucose levels between the control group and the intervention group after giving banana sinbiotic yogurt to mice with metabolic syndrome (Rahmawati et al, 2017).…”

“…According to (Dany et al, 2013) stated that men are more at risk of experiencing i-IFG than women. The adult population in the world who suffer from metabolic syndrome based on the International Diabetes Federation (IDF) is 20-25%, namely 8-24.2% in the male population and 7-46.5% in the female population (Rahmawati et al, 2017).…”

“…Probiotic consumption, compared with placebo, significantly reduced fasting glucose (MD = -0.31 mmol/L; 95% CI 0.56, 0.06; p = 0.02), fasting plasma insulin (MD = -1.29 μU/mL; 95% CI -2.17, -0.41; p = 0.004), and HOMA-IR (MD = 0.48; 95% CI -0.83, -0.13; p = 0.007) (Ruan et al, 2015). There was a significant difference in mean blood glucose levels between the control group and the intervention group after giving banana sinbiotic yogurt to mice with metabolic syndrome (Rahmawati, Djamiatun, & Suci, 2017). Probiotic yogurt is suggested as a nutritional approach in type 2 diabetes (T2D) and obesity (Barengolts et al, 2019).…”

UJI EFEKTIFITAS SINBIOTIK KEFIR TEPUNG PISANG BATU TERHADAP KADAR GLUKOSA DARAH DAN KADAR PROFIL LIPID TIKUS MODEL SINDROM METABOLIK Effectiveness Test of banana (Musa balbisiana) Flour Kefir Synbiotic on Blood Glucose Level and Lipid Profile Level in Metabolic Syndrome Rats Model

“…2017) dengan pemberian pakan standar dan aquadest ad libithum dengan tambahan HFFD (High Fat Fructose Diet) secara oral. HFFD berupa minyak babi 2ml/200g BB tikus/hari, kuning telur bebek 1ml/200g BB tikus/hari, dan fruktosa murni 1ml/200g BB tikus/hari (Rahmawati et al, 2017). Pemberian HFFD tidak memengaruhi asupan pakan standar yang dikonsumsi tikus.…”

“…Prebiotik akan difermentasi oleh Bakteri Asam Laktat (BAL) untuk menghasilkan SCFA (Verbeke et al, 2015) yang berperan dalam meningkatkan ekspresi dari glucose transporter 4 (GLUT-4) (Yan dan Kolapo, 2015). Peningkatan ekspresi GLUT-4 akan meningkatkan sensitivitas insulin dan peningkatan glukosa darah ke dalam membran sel sehingga terjadi penurunan kadar glukosa darah (Rahmawati et al, 2017). Penurunan kadar glukosa darah juga dapat menyebabkan perbaikan produksi insulin sehingga dapat memperbaiki kondisi obesitas sentral (Gandhi, 2017).…”