Pengaruh Variasi Konsentrasi Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa) Terhadap Stabilitas Fisik Sediaan Krim

Abstract

God's crown is one of the plants with various components with flavonoid as one of these components, which is an abundant plant metabolite component in nature that significantly functions for the plant's growth and antioxidants. This study aimed to examine The Concentration Variation Effect of 70% Ethanol Extract from God's Crown (Phaleria Macrocarpa) Towards The Physical Stability of Cream Preparations by variating the extract concentration. The formula concentration on the extract consists of FI (1%), FII (3%), FIII (5%), by stearic acid, paraffin liquid, alcohol cetyl, paraben propyl for the oil phase, aquadest, triethanolamine (TEA), and methylparaben for the water phase. Further evaluations include organoleptic test (smell, color, texture), pH test, homogeneity test, viscosity test, distribution test, and adhesion test. Each evaluation result found changes as intended by the research purpose, which is the effect of the extract's concentration variation on the physical stability of the cream preparations.

FORMULASI KRIM EKSTRAK DAUN SIRIH CINA (Peperomia Pellucida L.) DENGAN VARIASI KONSENTRASI TRIETANOLAMIN DAN ASAM STEARAT

“…Evaluasi ini dilakukan dengan menempatkan 1 g zat pada gelas ukur, kemudian zat tersebut menerima gelas yang sama tanpa beban kemudian letakan beban 200 g dengan selang waktu tertentu 1-2 menit dan diukur diameternya. (Ain Thomas, Tungadi, & Manoppo, 2022). Daya sebar 3-5 cm dikatakan semistiff sedangkan 5-7 cm dikatakan semifluid (Lestari, Hajrin, & Hanifa, 2020).…”

Comparing Antioxidant Activity of Extracts and Gel Preparations Combination of Buas-buas Leaves (Premna serratifolia l.) and Secang Wood (Caesalpinia sappan)

“…This color difference is based on the difference in the ratio of extract formulations used, F3 uses a more dominant concentration of crude extract so that it is yellowish green. The pH test of the 3 variations of the formula shows a pH value that is safe for the skin, because the appropriate pH requirements for topical preparations on the skin are in the pH range of 4-6.5 (Thomas et al, 2023). Based on the measurement of spreadability, the three formulas have different values and each value has not met the test requirements of 5-7 cm, but all formulas have adhesion that meets the requirements of more than 1 second (Sayuti, 2018;Yusuf et al, 2017).…”

Formulasi dan Uji Stabilitas Fisik Sediaan Hydrogel Eye Mask Ekstrak Etanol Kayu Secang (Caesalpinia sappan L)

“…Warna coklat pada formula 1, 2 dan 3 disebabkan karena warna ekstrak etanol kayu secang adalah warna coklat pekat, sehingga dapat dikatakan semakin besar jumlah ekstrak yang gunakan maka warna sediaan akan mendekati warna ekstrak yaitu coklat pekat. Hal ini didukung oleh penelitian Thomas et al (2022) yang mendapatkan bahwa semakin tinggi konsentrasi ekstrak yang digunakan maka semakin gelap/pekat warna sediaan. Berdasarkan beratnya, sediaan memiliki berat yang berbeda-beda hal ini dikarenakan perbedaan konsentrasi dari masing-masing sediaan, didapatkan bahwa semakin tinggi konsetrasi sediaan maka berat sediaan akan meningkat.…”