Pemphigus of the larynx

Wallner, Linden J.; Alexander, R. W.

doi:10.1288/00005537-196404000-00010

Cited by 9 publications

(6 citation statements)

References 6 publications

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“…Therefore, all dermatologists should be aware of which ENT manifestations might be present in patients with PV at some time during the course of this disease. Most of the data related to ENT manifestations in PV have been in reports of individual cases 3–17 . However, Hale and Bystryn 18 described laryngeal and/or nasal findings in 53 patients with PV, although only 11 underwent ENT examination.…”

Section: Discussionmentioning

confidence: 99%

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Ear, nose and throat manifestations in pemphigus vulgaris

España¹,

Fernández²,

Olmo³

et al. 2007

Br J Dermatol

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Section: Discussionmentioning

confidence: 99%

“…The frequency of ear, nose and throat (ENT) involvement in PV is not known. Only a few isolated individual cases have been reported, 3–17 most published in ENT journals. Recently, Hale and Bystryn 18 described laryngeal and nasal findings in 53 patients with PV, although only 11 underwent ENT examination.…”

mentioning

confidence: 99%

Ear, nose and throat manifestations in pemphigus vulgaris

España¹,

Fernández²,

Olmo³

et al. 2007

Br J Dermatol

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“…The frequency of the ear, nose and throat (ENT) involvement of PV is not clearly defined. There are some reports about laryngeal, pharyngeal, oesophageal, nasal and ear involvement in PV 3,4,7–10 . However, there are a few studies concerning the exact frequency of ENT mucosa involvement in PV 3,6 .…”

mentioning

confidence: 99%

Ear, nose and throat involvement in patients with pemphigus vulgaris: correlation with severity, phenotype and disease activity

Kavala¹,

Altıntaş²,

Kocatürk³

et al. 2011

Acad Dermatol Venereol

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Our results revealed that high number of patients with PV may present with active ENT lesions, furthermore patients with ear, nose and throat involvement may be asymptomatic and active lesions may be found in patients without any ENT symptoms. Therefore it should be considered that to understand the real extent of PV involvement, endoscopic ENT evaluation should be performed in patients with or without symptoms.

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“…[3][4][5][6] Only a few of the patients described in these reports underwent ENT evaluation, and reports of laryngeal lesions only describe their presence or absence. Our study is the first large series in which laryngeal lesions were reported according to their localisation in the larynx, and in which all patients with a diagnosis of pemphigus vulgaris underwent ENT endoscopic examination.…”

Section: Discussionmentioning

confidence: 99%

“…1 Laryngeal lesions due to pemphigus vulgaris are rarely reported, and the majority of such reports describe only the presence of such lesions, not their endoscopic location. [1][2][3][4][5][6] It is important to note that pemphigus vulgaris is a very rare disease with an estimated incidence of 0.7 patients per 100 000. The mean age of patients at the time of disease presentation is 40-50 years.…”

Section: Introductionmentioning

confidence: 99%

Laryngeal involvement in pemphigus vulgaris: a proposed classification

et al. 2012

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Objective: (1) To investigate the incidence of laryngeal involvement in a large series of patients with pemphigus vulgaris, using endoscopic examination, (2) to describe the lesions, and (3) to establish a classification of laryngeal involvement in pemphigus vulgaris based on the location of the lesions.Study design: Prospective study.Methods: A total of 40 sequentially treated pemphigus vulgaris patients, diagnosed using clinical, histological and immunofluorescence criteria, were evaluated for laryngeal manifestations using endoscopic examination. The results were used to establish a graded classification of laryngeal involvement according to the location of the lesions.Results: Active laryngeal lesions (ulcers or blisters) were found in 16 patients (40 per cent). Of these, 37.5 per cent were classified as grade I, 20 per cent as grade II, 20 per cent as grade III and 17.5 per cent as grade IV.Conclusion: Laryngeal involvement is common in pemphigus vulgaris and must be considered at the point of diagnosis. Grade I lesions are the most frequent.

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Pemphigus of the larynx

Cited by 9 publications

References 6 publications

Ear, nose and throat manifestations in pemphigus vulgaris

Ear, nose and throat manifestations in pemphigus vulgaris

Ear, nose and throat involvement in patients with pemphigus vulgaris: correlation with severity, phenotype and disease activity

Laryngeal involvement in pemphigus vulgaris: a proposed classification

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