Pemphigus. Epidemiologic and survival characteristics of 59 patients, 1955-1973

Krain, Lawrence S.

doi:10.1001/archderm.110.6.862

Cited by 86 publications

(63 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 The most common variant is pemphigus vulgaris. 2 Epidemiological studies from Israel 3 and the United States 4 suggest that Ashkenazi Jews have an increased risk for pemphigus, with annual incidence rates of 20 per 1million to 30 per 1 million, compared with other investigated populations such as those of Saudi Arabia 5 (2 per 1 million) and Bulgaria 6 (5 per 1 million).…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Variant Associated With Penicillin Use

Heymann¹,

Chodick²,

Kramer³

et al. 2007

Arch Dermatol

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Pemphigus Variant Associated With Penicillin Use

Heymann¹,

Chodick²,

Kramer³

et al. 2007

Arch Dermatol

View full text Add to dashboard Cite

“…The first study suggesting the role of viruses, principally herpes simplex, in the pathogenesis of pemphigus 4,14,15,25 was published in 1974. Since then case reports and research studies supporting this association have been published (Table 1).…”

Section: Introductionmentioning

confidence: 99%

Refractory pemphigus vulgaris associated with herpes infection: case report and review

Brandão

Fernandes

Batista

et al. 2011

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

SUMMARYBackground: Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering of the skin and mucosa, which develops due to the interaction between predisposing genetic and environmental factors. Infections caused by members of the Herpesviridae family have been suggested as a possible triggering factor for PV. Objective and Methods: In this report, we investigate the presence of herpesviruses in refractory lesions on the right upper eyelid. The lesion has persisted despite the treatment with corticosteroids. Polymerase chain reaction (PCR) and DNA sequence analysis have been used to detect the DNA of HSV 1/2, VZV, EBV, CMV, HHV-6, HHV-7, and HHV-8. Results: The sample collected from the right upper eyelid has tested positive for HSV 1/2. Sequence analysis has confirmed the PCR results and allowed the identification of the HSV strain as belonging to type 1. After treatment with acyclovir, the lesion of the right upper eyelid has cleared and not relapsed. Conclusion: When patients present PV lesions which are refractory to corticosteroid therapy, herpetic infection should be considered.

show abstract

“…Role of HSV in etiopathogenesis of pemphigus was first described by Krain in 1974 in an study on 59 patients where they found that after herpetic infection two patients developed pemphigus [5]. Schlupen et al reported 3 patients suffering from pemphigus vulgaris had exacerbation of oral mucosal lesion due to secondary herpes virus infection [6].…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Foliaceus with Herpes Simplex Virus;A Case Report

Bansal¹,

S²

2017

CMRA

View full text Add to dashboard Cite

Pemphigus foliaceus is an autoimmune disease having a chronic generalized course or may rarely present as an exfoliative dermatitis. Presence of occult HSV infection is involved in development of pemphigus and immunosuppressive therapy for pemphigus results in flare of typical or atypical herpetic lesions. We herein report of a case of a 48 year old male on immunosuppressive therapy for pemphigus foilaceous resulting in flare of herpetic infection.

show abstract

Pemphigus. Epidemiologic and survival characteristics of 59 patients, 1955-1973

Cited by 86 publications

References 11 publications

Pemphigus Variant Associated With Penicillin Use

Pemphigus Variant Associated With Penicillin Use

Refractory pemphigus vulgaris associated with herpes infection: case report and review

Pemphigus Foliaceus with Herpes Simplex Virus;A Case Report

Contact Info

Product

Resources

About