2009
DOI: 10.1002/nau.20858
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Pelvic organ prolapse and overactive bladder

Abstract: Aims: In this review we try to shed light on the following questions:. How frequently are symptoms of overactive bladder (OAB) and is detrusor overactivity (DO) present in patients with pelvic organ prolapse (POP) and is there a difference from women without POP? . Does the presence of OAB symptoms depend on the prolapsed compartment and/or stage of the prolapse? . What is the possible pathophysiology of OAB in POP? . Do OAB symptoms and DO change after conservative or surgical treatment of POP?Methods: We sea… Show more

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Cited by 161 publications
(172 citation statements)
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“…As soon as the woman feels wetting herself due to escape of urine, being embarrassed, reactive sympathetic activity reflex, will increase the sympathetic tone at the IUS to confirm its closure and preventing further leak of urine. This may explain the strong indications that there is a causal relationship between OAB and POP (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Thus by understanding this new concept, we can explain most of the voiding troubles.…”
Section: Second Stage Of Micturition: (Figure 1) 2mentioning
confidence: 96%
“…As soon as the woman feels wetting herself due to escape of urine, being embarrassed, reactive sympathetic activity reflex, will increase the sympathetic tone at the IUS to confirm its closure and preventing further leak of urine. This may explain the strong indications that there is a causal relationship between OAB and POP (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Thus by understanding this new concept, we can explain most of the voiding troubles.…”
Section: Second Stage Of Micturition: (Figure 1) 2mentioning
confidence: 96%
“…Following their publication, evidence was increasingly found that supported their claim that a correlation between the prolapse and an overactive bladder exists (de Boer et al 2010). …”
Section: Stability At the Bladder Base By A Tensioned Vaginal Wall Umentioning
confidence: 98%
“…19 The pathophysiology most likely to explain this relationship is bladder outlet obstruction, although other factors, such as activation of urothelial stretch receptors or bladder neck funnelling to allow urine to pool in the proximal urethra, may play a role. Following POP surgery, the impact on OAB is difficult to predict, and there is no reliable data to guide patient counselling in this regard; however, it clearly does resolve in many cases, 19 particularly with higher-stage prolapse.…”
Section: Pop For Urologistsmentioning
confidence: 99%