Peliosis hepatis and systemic lupus erythematosus: A rare condition identified by magnetic resonance imaging

Abstract

Peliosis hepatis is a rare benign disorder characterized by the presence of multiple cavities filled with blood with no preferential localization in the liver parenchyma. It may be related to several etiologic conditions, especially infections and toxicity of immunosuppressive drugs. To our knowledge, there are only three articles reporting the association between peliosis hepatis and systemic lupus erythematosus. In this report, we describe a case of this rare condition, highlighting the importance of magnetic resonance imaging. A short review of this subject is also presented.

A rare case of peliosis hepatis in primary immune deficiency

“…Lesions of peliosis hepatis can be suggested on imaging such as MRI combined with diffusion weighted imaging and positron emission tomography (PET)/CT. [13][14][15] Definitive diagnosis is still made using histopathology. These bloodfilled lesions can appear similar to hemangiomas on imaging, although hemangiomas highly over-express CD34, which is a marker for reticulin and fibrous tissue.…”

A Rare Case of Peliosis Hepatis in Infancy

“…The etiology of PH remains uncertain yet factors associated with it may be divided into: factors related to drug exposure such as steroids [4,5], immunosuppressants [6,7] as well as several toxins including alcohol [8]. Factors related to infectious diseases such as tuberculosis, HIV [9] and Bartonellahensalae [10], factors related to autoimmunity [11] and factors related to oncologic processes [12,13] are also associated with PH.…”