This study investigates the intricate dynamics between workplace spirituality, interpersonal trust, organizational justice, and mental well-being within the context of Integrated Islamic Schools (Sekolah Islam Terpadu - SIT) in West Java, Indonesia. Employing a mixed-method approach, combining theoretical and quantitative analyses, data from 261 educators across eight SITs are examined using partial least squares (PLS), structural equation modeling (SEM), and Likert-scale assessment. Results demonstrate the positive influence of organizational justice and workplace spirituality on interpersonal trust, ultimately impacting mental health, with interpersonal trust serving as a mediating factor. These findings underscore the importance of cultivating supportive work environments to enhance educators' well-being and effectiveness. The study contributes to understanding the factors influencing educators' mental health in Islamic educational settings, emphasizing the significance of trust-building strategies in fostering conducive learning environments. Future research endeavors in this realm can inform initiatives aimed at bolstering educator well-being and student outcomes. Theoretical implications highlight the pivotal roles of interpersonal trust, organizational justice, and workplace spirituality in shaping educators' mental health, emphasizing the importance of nurturing spirituality and equitable organizational practices to cultivate trust and enhance well-being. On a practical note, the study underscores the imperative of fostering supportive and fair work environments to promote trust and bolster educators' mental health, offering valuable insights for educators, administrators, and policymakers invested in prioritizing teachers' well-being.