The objective of this manuscript was to conduct an Integrative Literature Review on strategies for investigating and assessing self-efficacy in mentoring and e-mentoring processes. An electronic search of publications was conducted in the indexing bases: PubMed, BVS, SciELO and Scopus, between the period 2012 and 2022. The selected articles were organized into eight categories of analysis. The compilation of the findings indicated the existing interest in investigating these constructs around the world, in different areas of knowledge, with different audiences and different ways of measuring self-efficacy. It is relevant to resume the care needed for positive outcomes, given the focus of this literature review, of mentoring actions, both in relation to the design of the actions themselves, and in relation to the characteristics of those involved in them. Therefore, the sharing of experiences, in a scenario designed for this to occur in an appropriate manner, generates, in the individual who receives it, the improvement of the perception of his own capacity to successfully achieve his objectives and goals.