“…Of importance, even though trait anxiety and trait impulsivity are highly heritable, the specific form(s) of internalizing (e.g., panic, generalized anxiety, posttraumatic stress disorder) and externalizing (e.g., ADHD, conduct disorder, substance dependence) behavior that are exhibited by individuals who score high on these traits are determined by interactions between neurobiological vulnerabilities and environmental risk factors. For example, although impulsive male individuals who are reared in protective environments are likely to exhibit only ADHD (Beauchaine, Hinshaw, & Pang, 2010;Beauchaine & McNulty, 2013), their impulsivity often progresses to more serious externalizing conduct if they are reared in high-risk environments characterized by coercive parenting (e.g., Patterson, DeGarmo, & Knutson, 2000), coercive and deviant peer group affiliations (e.g., Dishion & Hiatt Racer, 2013;Snyder et al, 2008), and neighborhood violence and criminality (e.g., Meier, Slutske, Arndt, & Cadoret, 2008). Similarly, environmental risk, including child maltreatment and exposure to protracted stress, increase the likelihood of emerging anxiety and depressive disorders among those with specific genetic vulnerabilities, such as the short allele of the serotonin transporter and certain glucocorticoid polymorphisms (see, e.g., Beauchaine, Crowell, & Hsiao, 2015;Nugent, Tyrka, Carpenter, & Price, 2011;Stein, Schork, & Gelernter, 2008).…”