PEDIS grading and its role in diabetic foot ulcer management

Abstract

Background: Diabetic foot ulcer is the commonest cause of hospitalization in diabetic patients. Amputation is one of its dreaded complications, which deteriorates quality of life and increases mortality. Most of amputations are preventable and it is essential to define standard and efficient approach to treat diabetic foot ulcer in a timely manner. The first step is to define correct grade of diabetic foot ulcer and its risk of developing complications. Aim was to assess the outcome of treatment of diabetic foot ulcer with the given PEDIS score and to find the role of PEDIS score in predicting the outcome.Methods: This is a prospective cohort study. PEDIS score was calculated after all variables were categorized for a give patient and documented. PEDIS score was recorded for each patient. Patients followed up for 6 months and outcome was categorized as healed, unhealed, amputed, or death. Study was carried out till adequate sample size was achieved.Results: High PEDIS score in diabetic foot ulcer was associated with peripheral neuropathy. Adverse outcome like amputation and unhealed ulcer were more seen with high PEDIS score. All amputed patients were having high PEDIS score.Conclusions: PEDIS score is more useful in clinical practice for diabetic foot ulcer grading and can be uniformly applied to compare outcome all over the world.

A prospective observational study of role of pedis scoring in predicting complications of diabetic foot in a tertiary centre

“…Chinmay Gandhi et al showed the significant association between high PEDIS score and complications like amputation, non-healing ulcers. 5 So as our study also showed association between high score and complications in diabetic foot ulcer. According to Marie Louise Buhl Sorensen (32) et al, uncontrolled glucose level and presence of infection affects the healing process of ulcer.…”

“…5,29 In our study 95 patients with low score (0-7) had good outcome of healed ulcer who were managed by debridement. But some patients in spite of low score happened to have poor outcome like non-healing in 8 patients, amputation in 10 patients.…”

“…The primary goal of the study is to find the usefulness of PEDIS classification in diabetic foot ulcer, a study (PEDIS scoring and its role in management of diabetic foot ulcer) suggestive of PEDIS score <7 correctly picking up 87.5% of patients who had healed ulcer. 5 This is our background information for calculating the sample size. Using the following formula…”

“…This scoring has an excellent accuracy in grading the diabetic foot ulcer and helps in its management plan. 5 Diabetic foot ulcer is responsible for frequent hospital admissions and impairing quality of life. 6 In order to prevent further complications, the most accurate and globally accepted PEDIS scoring has come into play.…”

Comparison of vitamin D levels in diabetes mellitus patients with and without diabetic foot ulcers: An analytical observational study in Jakarta, Indonesia

“…6,10 It was observed that longer DFU duration and vitamin D deficiency had a significant negative effect on the rate of DFU healing, indicating DFU patients with lower serum vitamin D levels may have a higher PEDIS score. [11][12][13] In recent years, more reports have been reported on the role of vitamin D on T cell-mediated immunity, pancreatic insulin secretion, and its mechanism on cell growth and healing processes. 4 However, research on vitamin D in the Indonesian population is still limited.…”