Pediatric reference ranges on the Abbott IMx for FSH, LH, prolactin, TSH, T4, T3, freeT4, freeT3, T-uptake, IgE, and ferritin

Soldin, Steven J.; Morales, Antonio; Albalos, Fedee; Lenherr, Sara; Rifai, Nader

doi:10.1016/0009-9120(95)00038-5

Cited by 64 publications

(24 citation statements)

References 7 publications

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“…In males, the increase in hormone concentrations was smaller. Our findings agree with earlier studies [11,12]. Our findings for LH, FSH, TT3, and FT3 agree with earlier studies on the Abbott IMx [11].…”

Section: Resultssupporting

confidence: 93%

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Pediatric reference intervals for FSH, LH, estradiol, T3, free T3, cortisol, and growth hormone on the DPC IMMULITE 1000

Soldin

Hoffman

Waring

et al. 2005

Clinica Chimica Acta

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Background-We studied serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), triiodothyronine (T3), free T3 (FT3), cortisol and growth hormone (GH) concentrations in a population of pediatric patients. The reference intervals were determined separately for females and males stratified by age groups to assess age-and sex-related differences. Our objective was to obtain reference intervals for the 7 serum analytes for our pediatric population using the IMMULITE 1000 system. Methods-Serum samples of 800 in-and out-patients, newborn to 19 years old were analyzed using the DPC IMMULITE 1000 chemiluminescent immunoassay system.Results and conclusions-We report pediatric reference intervals for FSH, LH, E2, T3, FT3, cortisol, and GH. These reference intervals provide the basis for clinical interpretation of laboratory results using the IMMULITE 1000 system and the assessment of child development.

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Section: Resultssupporting

confidence: 93%

“…Our findings agree with earlier studies [11,12]. Our findings for LH, FSH, TT3, and FT3 agree with earlier studies on the Abbott IMx [11]. The data of Elmlinger utilized n values varying from 8 to 131 in the various age groups with many groups having an n<30 [12,13].…”

Section: Resultssupporting

confidence: 92%

Pediatric reference intervals for FSH, LH, estradiol, T3, free T3, cortisol, and growth hormone on the DPC IMMULITE 1000

Soldin

Hoffman

Waring

et al. 2005

Clinica Chimica Acta

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“…Blood lead concentrations < 10 μg/dl (0.48 μmol/l) can adversely affect the behavior and development of children [2]. Our group has more than two decades of experience in the area of pediatric reference ranges [3][4][5][6][7]. In order to define the current values for blood lead concentrations for both genders in the specific age groups, we calculated the pediatric concentration ranges for blood lead for age groups 0-12 months, 13-24 months, 2-4, 5-9, 10-11 and 12-18 years separately for female subjects and for male subjects.…”

Section: Introductionmentioning

confidence: 99%

Blood lead concentrations in children: new ranges

Hanak

Soldin

2003

Clinica Chimica Acta

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Background-Lead exposure in young children may have adverse neurodevelopmental effects. Currently, an increased blood lead concentration is defined as ≥10 μg/dl for males and females of all ages, including children younger than 6 years. Using a large hospital population (n = 11,145), we define more specific ranges for pediatric blood lead concentrations.Methods-Pediatric blood lead concentrations were determined (atomic absorption spectrophotometry) on patient samples accrued from January 2001 to June 2002, and the data was analyzed employing the Hoffman approach.Results-For lead, the 2.5th and 97.5th percentiles for subjects aged 0 to 12 months were 2.3 to 4.7 μg/dl for females and 1.8 to 4.9 μg/dl for males. The 97.5th percentiles increased for the 1-2 years age group both for females (5.2 μg/dl) and males (5.6 μg/dl). There was a significant decrease in blood lead concentrations after age 10 years, the 97.5th percentile being 4.4 μg/dl in both female and male subjects. The values in all corresponding age groups were similar for females and for males. The medians of all age groups were similar for females and for male subjects. Conclusion-The blood lead concentrations are much lower compared to previously published data.

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“…Given the important role of these hormones in sexual development, cir-culating concentrations can differ between the neonatal period, early childhood, prepubertal years, and puberty, reflecting developmental and maturation processes of various organs and tissues (2, 4 -6 ). In addition, important differences are also found between the hormone concentrations observed in boys and girls (5)(6)(7)(8). As such, it is critically important that pediatric reference intervals are established that reflect these changes (i.e., partitioned according to age, sex, and developmental stage) to aid in differentiating between healthy children and those in need of further medical follow-up.…”

confidence: 99%

Complex Biological Pattern of Fertility Hormones in Children and Adolescents: A Study of Healthy Children from the CALIPER Cohort and Establishment of Pediatric Reference Intervals

et al. 2013

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BACKGROUND:Pediatric endocrinopathies are commonly diagnosed and monitored by measuring hormones of the hypothalamic-pituitary-gonadal axis. Because growth and development can markedly influence normal circulating concentrations of fertility hormones, accurate reference intervals established on the basis of a healthy, nonhospitalized pediatric population and that reflect age-, gender-, and pubertal stage-specific changes are essential for test result interpretation.

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Pediatric reference ranges on the Abbott IMx for FSH, LH, prolactin, TSH, T4, T3, freeT4, freeT3, T-uptake, IgE, and ferritin

Cited by 64 publications

References 7 publications

Pediatric reference intervals for FSH, LH, estradiol, T3, free T3, cortisol, and growth hormone on the DPC IMMULITE 1000

Pediatric reference intervals for FSH, LH, estradiol, T3, free T3, cortisol, and growth hormone on the DPC IMMULITE 1000

Blood lead concentrations in children: new ranges

Complex Biological Pattern of Fertility Hormones in Children and Adolescents: A Study of Healthy Children from the CALIPER Cohort and Establishment of Pediatric Reference Intervals

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