Pediatric odontogenic fibromyxoma of the mandible: Case report and review of the literature

Haser, Grace C.; Su, Henry; Hernández-Prera, Juan C.; Khorsandi, Azita S.; Wang, Beverly Y.; Urken, Mark L.

doi:10.1002/hed.24090

Cited by 13 publications

(30 citation statements)

References 31 publications

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“…They can occur anywhere in the jaws but have a predilection for the molar and premolar regions [4]. Odontogenic myxomas are rarely observed in children under 10 years of age [14]. Consistent with our case, swelling is the most common clinical feature [10].…”

Section: Odontogenic Fibromyxoma Demographics and Clinical Presentationsupporting

confidence: 88%

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Fibromyxoma of the Jaw: Case Report and Review of the Literature

Alhousami

Sabharwal

Gupta

et al. 2017

Head and Neck Pathol

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We report a case of fibromyxoma of the mandible, a rare benign odontogenic tumor. Our patient presented in the first trimester of pregnancy with a large mass in the right body of the mandible exhibiting displacement of teeth and destruction of an extensive area of the mandibular bone. The mass was biopsied and diagnosed as a fibromyxoma. The large size of the tumor dictated a wide mandibular resection. We will review the clinical, radiographic, and histologic features of fibromyxoma and discuss its differential diagnoses. In addition, we will provide an overview of patient management. Fibromxyoma is a benign gnathic tumor that can be locally aggressive. To ensure appropriate treatment, it is important to distinguish this neoplasm from other mimickers in which myxoid, spindle mesenchymal cell proliferation is prominent.

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Section: Odontogenic Fibromyxoma Demographics and Clinical Presentationsupporting

confidence: 88%

“…Fibromyxomas express vimentin and are typically negative for S-100, CD34, SMA, and CD68 [19]. A summary of the reported demographics and histopathological characteristics of odontogenic fibromyxomas published within the last 10 years is provided in Table 1 [14,18,[20][21][22][23][24][25][26].…”

Section: Gross and Histopathologic Characteristics Of Fibromyxomamentioning

confidence: 99%

Fibromyxoma of the Jaw: Case Report and Review of the Literature

Alhousami

Sabharwal

Gupta

et al. 2017

Head and Neck Pathol

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“…Owing to high recurrence rate after conservative treatment and considerable debate on its appropriate treatment, complete surgical resection is the standard approach for the management of this tumour 18 19. An extensive search of the literature on the management of these tumours showed 45.5% of mandibular cases were treated surgically by enucleation, curettage or enbloc resection 1 9 18–20.…”

Section: Discussionmentioning

confidence: 99%

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Bahl¹,

Raju²,

Shah

et al. 2016

BMJ Case Reports

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Myxoma of the jaws which was first described by Thoma and Goldman in 1947 is a rare neoplasm and its rate of prevalence and incidence is not available. Myxoma term, according to 1992 WHO classification, is used along with odontogenic myxoma (OM) and myxofibroma. There are two forms of myxomas or fibromyxomas that are recognised in head and neck region: one is derived from the facial skeleton and the other is derived from the soft tissue. Most of the OM are located intraosseously, but peripheral ones are also recognised. OM behaves differently from myxomatous tumours of long bones, which recur more often and may transform into malignancy. A majority of these lesions occur between 2nd and 4th decade. In the pathogenesis of OM, dental papilla, dental follicle and periodontal ligament tissues have been implicated as possible 'germ centres'. This case describes an uncommon finding of central odontogenic fibromyxoma, throwing light on its epidemiology, clinical, histopathology, molecular and treatment aspects.

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“…De acuerdo a la literatura, el FM representa del 2,3 al 17,7 % de todos los tumores odontogénicos, con una mayor frecuencia en mujeres (Reddy et al; Kant et al). El FM tiende a desarrollarse en adultos jóvenes entre los 25-30 años de edad, con un pico de incidencia de 28 años, siendo rara su aparición en individuos menores de 10 años o mayores de 50 (Meleti et al;Haser et al, 2016). Con relación a su localización, existe una ligera predilección por presentarse en la región posterior de la mandíbula, y es poco frecuente la afectación de la región anterior o la maxila (Haser et al; Zayet et al) en donde tiene un comportamiento más agresivo, pudiendo involucrar el hueso cigomático, seno maxilar e inclusive la órbita (Gupta et al; Kant et al; Reddy et al).…”

Section: Discussionunclassified

Fibromixoma Odontogénico Agresivo en Maxila: Abordaje Quirúrgico

Guillen-Rivera¹,

Ortega-Pertuz

Espina-Suárez³

2019

Int. J. Odontostomat.

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RESUMEN: El fibromixoma odontogénico (FM) es una infrecuente lesión benigna que muestra un comportamiento invasivo. Considerada una variante del mixoma odontogénico, presenta un origen mesenquimal controvertido y ligera predilección por el sexo femenino. La lesión está asociada a zonas con estructuras dentales adyacentes, siendo su localización más frecuente la región mandibular posterior. El objetivo de este trabajo fue mostrar un caso agresivo de FM en una paciente, localizado en la zona posterior de maxila, destacando su abordaje quirúrgico. Se reporta un caso de una mujer de 52 años, la cual acudió a la consulta por presentar una masa indolora, firme a la palpación en el lado derecho de la maxila. Radiográficamente se observaba como una imagen radiopaca, de márgenes mal definidos que se extendía en el seno maxilar ipsilateral; la tomografía computarizada pudo evidenciar la expansión de las paredes del antro y la fosa nasal, con compromiso del cigomático y el piso de órbita. Se realizó biopsia incisional y el diagnóstico histopatológico fue de FM. El tratamiento de elección consistió en la resección en bloque,mediante abordaje Weber-Fergusson, acompañada de reconstrucción con placa y malla de titanio para garantizar la suspensión del globo ocular; un nuevo estudio histopatológico, confirmó el diagnóstico inicial. Al año del procedimiento quirúrgico no se evidenció recidiva, observando que el material de reconstrucción mantiene su posición, proporcionado estética y funcionabilidad a la paciente.

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Pediatric odontogenic fibromyxoma of the mandible: Case report and review of the literature

Cited by 13 publications

References 31 publications

Fibromyxoma of the Jaw: Case Report and Review of the Literature

Fibromyxoma of the Jaw: Case Report and Review of the Literature

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Fibromixoma Odontogénico Agresivo en Maxila: Abordaje Quirúrgico

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