Deterioration of mental health is an extremely important risk factor for sexual dysfunction. The aim is to investigate sexual dysfunction in patients with neurotic mental disorders. Material. Peculiarities of sexual dysfunctions in 256 patients (120 men and 136 women) were analyzed. Research. Assessment of sexual dysfunctions was performed on the basis of individual interviews and questionnaires of each patient. Intimate disorders such as perversion, anorgasmia, deactualization, hypoaesthesia, hyperesthesia, decreased libido, alibidemia, decreased sexual activity, abstinence, decreased erection, premature ejaculation, and pain during sex were evaluated. Conclusions. The issue of sexual disorders in various forms of neurosis is an extremely relevant topic, as these disorders cause significant disharmony in different areas of life of patients. Not only does it not lose its relevance, but it is gaining more and more medical and social significance.