Pectin grafted poly(<i>N</i>‐vinylpyrrolidone): Optimization and <i>in vitro</i> controllable theophylline drug release

Fares, Mohammad M.; Assaf, Shereen M.; Abul‐Haija, Yousef M.

doi:10.1002/app.32172

Cited by 47 publications

(26 citation statements)

References 32 publications

(25 reference statements)

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“…Such results clearly demonstrated that pectin is strongly bonded to polycaprolactone in large amounts of crystalline PGP that decomposed at 400°C, and consequently, very small amounts of amorphous PGP exist. In previous works, amorphous or low‐crystalline pectin grafted polymers showed split of decomposition peaks of pectin and other polymers . Such results came in accordance with high percentage of crystallinity of PGP determined in DSC results and also with ATR‐FTIR results.…”

Section: Resultssupporting

confidence: 87%

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π‐Plasmon absorbance films of carboxylic functionalized CNTs coupled with renewable PGP platforms

Fares

2018

Polymers for Advanced Techs

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π‐Plasmon absorbance films of carboxylic functionalized multiwall carbon nanotubes (CNTs) coupled with renewable and recycled polycaprolactone grafted pectin (PGP) platforms as successful alternative for ordinary nondegradable platforms were investigated. Characterization of the synthesized carboxylic functionalized CNTs was performed using 1H NMR and attenuated total reflectance Fourier transform infrared for structural identification, thermogravimetric analysis and derivative thermogravimetric analysis for thermal stability, and X‐ray powder diffraction for crystal structure, whereas the characterization of prepared PGP was done by means of attenuated total reflectance Fourier transform infrared for chemical structure, differential scanning calorimetry for melting endotherms of polycaprolactone and high crystalline structure of PGP, and thermogravimetric analysis and derivative thermogravimetric analysis for thermal stability of PGP. Fabrication of water‐dispersed carboxylic functionalized CNTs coupled with PGP films was performed by casting technique in the presence of Ca2+ as cross‐linker. The thin films were tested for π‐plasmon absorbance using UV‐Vis spectrometry. Different fractions of carboxylic functionalized CNTs and PGP films demonstrated π‐plasmon absorbance broad peaks at λmax = 232 nm, which corresponded to 5.36 eV. The fabrication of novel films from renewable recycled PGP platform and advanced carboxylic functionalized CNTs properties will be the key features for many of next forthcoming technologies. The PGP considered as environment‐friendly and easily degradable platforms will be a successful alternative for conventional nondegradable electronic platforms, and water‐dispersed carboxylic functionalized CNTs with advanced properties will be finding accelerating executive applications.

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Section: Resultssupporting

confidence: 87%

“…In previous works, amorphous or low-crystalline pectin grafted polymers showed split of decomposition peaks of pectin and other polymers. [50][51][52] Such results came in accordance with high percentage of crystallinity of PGP determined in DSC results and also with ATR-FTIR results.…”

Section: High Crystalline and High Thermally Stable Pgpsupporting

confidence: 88%

π‐Plasmon absorbance films of carboxylic functionalized CNTs coupled with renewable PGP platforms

Fares

2018

Polymers for Advanced Techs

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“…The results were analyzed using Xpert high score (version 1.0 b, Philips analytical B.V.). The % crystallinity of the samples was determined as per the equation given below19: …”

Section: Methodsmentioning

confidence: 99%

Lanolin‐based organogels as a matrix for topical drug delivery

Sagiri

Behera

Pal

et al. 2012

J of Applied Polymer Sci

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The current study deals with the development of lanolin‐based emulsion gels by hot emulsification method. Bright‐field, phase contrast, and fluorescent micrographs of the gels have shown the uniform distribution of circular water droplets in the formulations. Coalescence of water droplets was observed in gels containing higher proportion of water. Fourier transform infrared spectrophotometric studies indicated absence of Ln‐drug chemical interactions. X‐ray diffraction studies suggested an increase in amorphousness of the gels with the incorporation of water into the gel structure. The salicylic acid (SA), model drug, release from the gels was found to follow Higuchi kinetics. Krossmeyer–Peppas model fitting indicated non‐Fickian release of the drug. As the water content of the gels increased, there was a corresponding increase in the rate of release of the drug. The gels showed non‐Newtonian and thixotropic flow behavior. The gel to sol transition and melting temperatures of the gels were identified by differential scanning calorimetric (DSC) thermal analysis and falling ball method. DSC thermograms indicated an increase in thermal stability with the increase of water content in the gels. The gels showed sufficient spreadability and biocompatibility characteristics to be used as topical formulations. SA loaded gels showed good antimicrobial efficacy against Bacillus subtilis, a Gram‐positive bacterium. Based on the preliminary studies, the developed gels may be regarded as carriers in topical drug delivery. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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“…Furthermore, the area under the curve was used to observe the ratio of aliginic acid to poly(methacrylamide) fractions in the formed hydrogel as depicted in Fig. . It can be seen that aliginic acid shows a sharp decomposition temperature peak at 242 °C (Fig.…”

Section: Resultsmentioning

confidence: 99%

Environmentally friendly copolymeric beads of Chlorella vulgaris and poly(methacrylamide) grafted aliginic acid di‐block copolymers for biosorption of zinc ions

Fares

Al‐Rub

Kandah

et al. 2012

Polymer International

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The synthesis of biodegradable environmentally friendly copolymeric beads for water treatment biosorption processes is demonstrated. The synthesized poly(methacrylamide) grafted aliginic acid copolymers were characterized using 1H NMR, Fourier transform infrared spectroscopy, TGA and SEM. The di‐block copolymers showed a morphological change from two‐dimensional layer‐by‐layer structures to three‐dimensional well‐compacted wrinkles as grafting efficiency increased. The copolymeric beads were formed from the di‐block copolymer and algae crosslinked with 5% calcium ions (w/w). These copolymeric beads were then subjected to biosorption investigations for zinc ions as a model heavy metal ion at different pH values and stirring time periods. Batch adsorption experiments showed that the copolymeric beads were effective in zinc ion removal from aqueous solutions with maximum uptake exceeding 89.0 mg g–1 using higher grafting efficiency copolymeric beads at pH 5.5. Equilibrium pH studies revealed that zinc biosorption was pH dependent and maximum uptake was obtained at pH 5.5. Dynamics studies showed that the biosorption of zinc was rapid with equilibrium attained within 40 min and the data followed pseudo‐second‐order kinetics. The equilibrium biosorption of zinc ions on the copolymeric beads exhibited a Freundlich isotherm fit. © 2012 Society of Chemical Industry

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Pectin grafted poly(N‐vinylpyrrolidone): Optimization and in vitro controllable theophylline drug release

Cited by 47 publications

References 32 publications

π‐Plasmon absorbance films of carboxylic functionalized CNTs coupled with renewable PGP platforms

π‐Plasmon absorbance films of carboxylic functionalized CNTs coupled with renewable PGP platforms

Lanolin‐based organogels as a matrix for topical drug delivery

Environmentally friendly copolymeric beads of Chlorella vulgaris and poly(methacrylamide) grafted aliginic acid di‐block copolymers for biosorption of zinc ions

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