Pecoma of the lung: a benign tumor with extensive 18F-2-deoxy-D-glucose uptake

Zarbis, Nikolaos; Barth, Thomas F.E.; Blumstein, N.; Schelzig, Hubert

doi:10.1510/icvts.2007.154039

Cited by 27 publications

(20 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only few cases have reported the interval growth of CCTLs. However, previous reports only stated an interval growth without mentioning the exact change in size (9,12) or suggested a maximum volume doubling time estimated from initial normal chest radiograph (13). No previous reports remarked on serial imaging follow up of CCTL.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Growth pattern change of a benign clear cell ‘sugar’ tumor of the lung: Serial imaging surveillance over seven years

et al. 2018

View full text Add to dashboard Cite

Clear cell tumor of the lung is a rare benign mesenchymal tumor and only sporadic cases have been previously reported. The present study reports the case of a 58-year-old man who presented with an incidentally detected solitary pulmonary nodule. Based on comparisons with serial previous chest and spine radiographs, a growth pattern change in the nodule (initial gradual growth over 4.5 years, then recent no growth over 2.5 years) was identified. The nodule was diagnosed as a benign clear cell tumor of the lung (CCTL) following surgical resection. Few studies have previously reported interval growth of CCTLs and the growth pattern of CCTL is not yet well known. To the best of our knowledge, this is the first reported case in which the growth pattern change of CCTL was identified via serial imaging over 7 years of follow-up.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Because of the rich vascular stroma, most CCTLs show homogenous intense enhancement on CT scans. Kim et al (8), reported an early wash-in and washout pattern of CCTL on dynamic CT. CCTLs usually show no 18 F-2-deoxy-D-glucose (FDG) uptake, but a 2.8-cm benign CCTL that showed extensive FDG uptake has been reported (9).…”

Section: Discussionmentioning

confidence: 99%

Growth pattern change of a benign clear cell ‘sugar’ tumor of the lung: Serial imaging surveillance over seven years

et al. 2018

View full text Add to dashboard Cite

show abstract

“…That is exactly the reason why long-term follow-up of PEComa's is recommended. Some studies reported possible use of positron emission tomography in tumor follow-up (16).…”

Section: Discussionmentioning

confidence: 99%

Perivascular Epithelioid Cell Tumor of the Kidney: A Rare Case Report

Karakoç¹,

Çelik²,

Bozkurt³

et al. 2017

jus

View full text Add to dashboard Cite

IntroductionPerivascular epithelioid cell tumors (PEComas) of the kidney are a group of tumor family covering classical angiomyolipoma (AML), microscopic AML (microhamartoma), intraglomerular lesions, cystic AML, epithelioid AML, oncocytoma-like AML and lymphangiomyomatosis of the renal sinus. The World Health Organization (WHO) defines PEComa as a "mesenchymal tumor that contains perivascular epithelioid cells presenting histological and immunohistochemical differences". While classical AML is benign, epithelioid AMLs are defined as potentially malign mesenchymal lesions for their capacity to develop local recurrence and metastasis (1,2,3). Surgical treatment may be required in AML for symptoms such as hemorrhage and pain, or for the risk of malignancy in tumors that cannot be differentiated from AML in the case of PEComa and certain variants of AML (3,4,5).This case report aimed to present a patient who undergone retroperitoneoscopic partial nephrectomy due to a renal mass and diagnosed with PEComa after pathological examination. Case PresentationWe planned magnetic resonance imaging (MRI) in a 25-year-old male patient, who was admitted to our clinic due to left-sided flank pain, with no pathological finding during the examination and laboratory tests, however, with a suspicious mass lesion located at the inferior pole of the left kidney detected during ultrasonographic examination. It was decided to perform surgical excision after detection of a 4 cm tumoral lesion in the inferior pole of the left kidney on MRI (Figure 1). We performed left retroperitoneoscopic partial nephrectomy in our clinic. The total operative time was 90 minutes with the warm ischemia time Böbreğin perivasküler epiteloid hücre tümörleri nadir görülen histolojik ve immünohistokimyasal olarak farklı perivasküler epiteloid hücrelerden oluşan mezenkimal tümörlerdir. Çoğunluğu benign tümörlerdir; fakat malign olanları agresif seyredebilir ve metastaza yol açabilir. Standart tedavi yöntemi ise cerrahi eksizyondur. Olgumuzda 25 yaşında sol böbrek alt polünde 4 cm kitle saptanan ve cerrahi olarak eksize ettiğimiz hastayı sunmayı amaçladık. Anahtar Kelimeler: Böbrek tümörü, perivasküler epiteloid hücre tümörü, parsiyel nefrektomi Perivascular epithelioid cell tumors are rare mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. They are mostly benign, however, malignant tumors with aggressive behavior and distant metastasis can also occur. The standard treatment is surgical excision. Here, we report a case of a 25-year-old male with a 4 cm-mass located in the inferior pole of the left kidney, treated by surgical excision.

show abstract

“…[9–12] Certain clinicopathologic features such as a diameter >2.5 cm, the presence of symptoms, and extensive necrosis or abundant mitoses visible under an optical microscope are correlated with more aggressive behavior. [13–15] Surgical resection is an acceptable curative approach for CCTL, as the tumor's benign behavior is not invariable, and chemotherapy or radiotherapy has not demonstrated significant benefits for malignant CCTL. [16] …”

Section: Discussionmentioning

confidence: 99%

Clear cell tumor of the lung

Qian

Lu²,

Li³

et al. 2016

Medicine

View full text Add to dashboard Cite

Background:Clear cell tumor of the lung (CCTL) is a rare and mostly benign pulmonary tumor arising from perivascular epithelioid cells. We reported 2 cases of CCTL in a 24-year-old man with chest pain and a 59-year-old man with dyspnea.Methods:Their chest CT images revealed a well-defined, homogeneous nodule located in the peripheral region of lung parenchyma. The solid nodule showed intense heterogenous postcontrast enhancement in the arterial phase and a homogenous appearance in the venous phase. The two patients underwent thoracotomy, and pathological examinations, including immunohistochemical studies revealed that both cases were benign clear cell tumors.Results:Due to the fact that only a few cases about CCTL were reported, clinicopathological aspects and radiological characteristics of this type of tumor are not well established.Conclusion:CCTL is a rare and benign primary tumor and majorly occurs in middle-aged and elder people. The finding of a small vessel extending along and partially wrapping up one side of the mass in the CT-enhanced images might be a helpful feature to differentiate CCTL from other lung neoplasms.

show abstract

Pecoma of the lung: a benign tumor with extensive 18F-2-deoxy-D-glucose uptake

Cited by 27 publications

References 8 publications

Growth pattern change of a benign clear cell ‘sugar’ tumor of the lung: Serial imaging surveillance over seven years

Growth pattern change of a benign clear cell ‘sugar’ tumor of the lung: Serial imaging surveillance over seven years

Perivascular Epithelioid Cell Tumor of the Kidney: A Rare Case Report

Clear cell tumor of the lung

Contact Info

Product

Resources

About