“…Peak compression of clevidipine in packed supercritical fluid chromatography has been previously investigated, optimised and reported using typical analytical conditions [6,19,20]. It was shown that, after a chemometric optimisation of chromatographic parameters, when a 5 pL injection of clevidipine (0.2 mg mL -~) prepared in 70 % water, which corresponds to approximately 0.001 mg of sample injected, efficiencies of 135,000 were possible on a 200 • 4.6 mm ID packed column [19].…”