PDMS Microlenses for Optical Biopsy Microsystems

Ribeiro, J. F.; Costa, Adriana; Gomes, J. M.; Costa, Carlos A. Bana e; Goncalves, S. B.; Wolffenbuttel, R.F.; Correia, J. H.

doi:10.1109/tie.2017.2716874

Cited by 13 publications

(18 citation statements)

References 26 publications

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“…[22] Because the spatial representation is not very practical, a planar diagram is used to evaluate the colour stimulus in terms of tone and richness. The following applies to trichromatic coordinates (4) ,…”

Section: Methodsmentioning

confidence: 99%

“…In the 3D printing technology using the method of DPL (Digital Light Processing), it is used for the production of a printing base and is also widely used for fine lithography techniques, especially for the creation of microfluidic and microengineering systems -MEMS (Micro Electro Mechanical Systems). For example, the authors of the publication [4] describe an optical biopsy microsystem technology that has smaller dimensions (11.2 x 18.6 mm) compared to other systems and reduced power consumption. The microsystem includes an image magnification optical microsystem (IMOM) and light emitting diodes (LED).…”

Section: Introductionmentioning

confidence: 99%

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Thermal analysis of PDMS light bulbs with a luminophore

Novák

Nedoma

Fajkus

et al. 2018

ELECTROTECHNICAL REVIEW

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This article focuses on the production and measurement of incandescent lamps made from polydimethylsiloxane and YAG luminophore. By a suitable combination of these materials along with a light source of a specific wavelength, white colour of light can be achieved. Since the optical power from the light source is fed through a light guide structure to a remote lighting section, the device can be used in hazardous environments such as mines or factories where electromagnetic interference is likely to occur. The study describes temperature characteristics and chromaticity temperature changes of the designed lamp for different luminophore concentrations. Streszczenie. W artykule analizuje sie lampy wykonane z polydimethylsiloxanu PDMS z luminoforem YAG. W lampach tych można osiągnąć białą barwę dzięki odpowiedniej kombinacji materiału. Dzięki odpowiedzniej konstrukcji lampy te można używać w środowiskach niebezpiecznych jak kopalnie. W artykule analizowano temperaturę I barwę światła dla różnych luminoforów. Analiza termiczna lamp PDM z luminoforem.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Thermal analysis of PDMS light bulbs with a luminophore

Novák

Nedoma

Fajkus

et al. 2018

ELECTROTECHNICAL REVIEW

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“…[22][23][24][25] To fabricate this elastomeric lens, the droplet-based fabrication techniques are especially popular as they offer a simple and fast fabrication process. [25,[32][33][34][35][36] In the injection method, the liquid PDMS is injected on top of a substrate and cured with a heating treatment. Currently, there are two popular ways to fabricate the lens with PDMS droplet on a substrate including the upright injection [26][27][28][29][30][31] and hanging method.…”

Section: Pdms Lens Fabricationmentioning

confidence: 99%

Portable Smartphone‐Based Platform for Real‐Time Particle Detection in Microfluidics

Salafi

Zeming

Lim

et al. 2018

Adv Materials Technologies

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Real‐time particle detection is an integral part of microfluidics for diagnostics. The detection method is typically performed with the use of bulky and expensive instruments including a bench‐top microscope, high‐speed camera, and fluidic pump. This limits the practical applications of microfluidics for real‐time point‐of‐care detection. Here, a portable and low‐cost smartphone microscopy platform is developed for real‐time particle detection in microfluidics based on a polydimethylsiloxane (PDMS) lens, modular 3D printed accessory, plug‐and‐play paper pump, and a novel particle counting algorithm. The PDMS lens is developed using a new method based on the PDMS precuring and hydrophobic modification on a pillar template to allow for fabrication of various lens shapes with high reproducibility and broad range magnification ratio from 30× to 100×. The modular 3D printed smartphone accessory allows for easy imaging setup to cater for different size of microchannel and the paper pump design provides a convenient single‐step process to drive the fluid. The platform is implemented to count the moving particles in the outlet of microfluidics deterministic lateral displacement with 94% counting accuracy. This platform provides huge potential applications for real‐time point‐of‐care detection that can be integrated with various microfluidic techniques.

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“…Contrary to this method, fabrication of a PDMS µ-lens by the hanging droplet method does not require temperature processes and allows a control on the µ-lens specifications (thickness, focal point, etc.) due to the volume of the PDMS solution [ 26 ]. The PDMS biocompatible polymer was chosen due to the following characteristics [ 26 , 27 ]: (1) strong adhesion and internal cohesion; (2) good optical properties, i.e., a refractive index of approximately 1.4 (below 1600 nm) [ 28 ]; (3) optical transparency in the visible region (>95%); and (4) Young’s modulus of 1 MPa.…”

Section: Introductionmentioning

confidence: 99%

“…due to the volume of the PDMS solution [ 26 ]. The PDMS biocompatible polymer was chosen due to the following characteristics [ 26 , 27 ]: (1) strong adhesion and internal cohesion; (2) good optical properties, i.e., a refractive index of approximately 1.4 (below 1600 nm) [ 28 ]; (3) optical transparency in the visible region (>95%); and (4) Young’s modulus of 1 MPa. The flexibility and transparency of this polymer also enables its use as a micro-electro-mechanical systems (MEMS) substrate or for microfluidic devices [ 29 , 30 , 31 ].…”

Section: Introductionmentioning

confidence: 99%

PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics

Costa

Pimenta

Ribeiro

et al. 2019

Sensors

Self Cite

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Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis.

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PDMS Microlenses for Optical Biopsy Microsystems

Cited by 13 publications

References 26 publications

Thermal analysis of PDMS light bulbs with a luminophore

Thermal analysis of PDMS light bulbs with a luminophore

Portable Smartphone‐Based Platform for Real‐Time Particle Detection in Microfluidics

PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics

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