Pdb21 a Cost-Utility Analysis of Insulin Glargine (Lantus®) in the Treatment of Patients With Type 1 Diabetes

Kristensen, FK; Sverre, JM; Bustad, S

doi:10.1016/s1098-3015(10)61744-5

Cited by 4 publications

(3 citation statements)

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“…Their excellent mechanical properties, outstanding biocompatibility, and low density make them ideal materials for 3D printing [ 70 ]. Over the past 20 years, SLM, SLS, EBM, and DMLS have been introduced as promising manufacturing technologies for Ti and its alloys [ 71 , 72 , 73 , 74 , 75 , 76 , 77 ]. Owing to their excellent reproducibility, flexibility in design, relatively good resolution, and low-cost effectiveness, these 3D printing methods are widely used to manufacture implantable devices (i.e., dental implants and scaffolds) and prosthetic devices (i.e., dental crowns and denture frameworks) based on Ti and its alloys [ 69 , 78 , 79 , 80 ].…”

Section: Three-dimensional Printing Materialsmentioning

confidence: 99%

“…At present, medical devices based on Ti and its alloys have been used to fabricate personalized mandibular implants for maxillofacial surgery (Figure 2A) [84]. technologies for Ti and its alloys [71][72][73][74][75][76][77]. Owing to their excellent reproducibility, flexibility in design, relatively good resolution, and low-cost effectiveness, these 3D printing methods are widely used to manufacture implantable devices (i.e., dental implants and scaffolds) and prosthetic devices (i.e., dental crowns and denture frameworks) based on Ti and its alloys [69,[78][79][80].…”

Section: Ti and Its Alloysmentioning

confidence: 99%

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Dental Materials Applied to 3D and 4D Printing Technologies: A Review

Cai

et al. 2023

Polymers

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As computer-aided design and computer-aided manufacturing (CAD/CAM) technologies have matured, three-dimensional (3D) printing materials suitable for dentistry have attracted considerable research interest, owing to their high efficiency and low cost for clinical treatment. Three-dimensional printing technology, also known as additive manufacturing, has developed rapidly over the last forty years, with gradual application in various fields from industry to dental sciences. Four-dimensional (4D) printing, defined as the fabrication of complex spontaneous structures that change over time in response to external stimuli in expected ways, includes the increasingly popular bioprinting. Existing 3D printing materials have varied characteristics and scopes of application; therefore, categorization is required. This review aims to classify, summarize, and discuss dental materials for 3D printing and 4D printing from a clinical perspective. Based on these, this review describes four major materials, i.e., polymers, metals, ceramics, and biomaterials. The manufacturing process of 3D printing and 4D printing materials, their characteristics, applicable printing technologies, and clinical application scope are described in detail. Furthermore, the development of composite materials for 3D printing is the main focus of future research, as combining multiple materials can improve the materials’ properties. Updates in material sciences play important roles in dentistry; hence, the emergence of newer materials are expected to promote further innovations in dentistry.

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Section: Three-dimensional Printing Materialsmentioning

confidence: 99%

Section: Ti and Its Alloysmentioning

confidence: 99%

Dental Materials Applied to 3D and 4D Printing Technologies: A Review

Cai

et al. 2023

Polymers

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“…Recently, an increasing number of studies have involved the development of novel biomaterials with various active ingredients for the prevention of pressure ulcers [11][12][13]. Among them, flavonoids containing baicalin have demonstrated anti-inflammatory, anti-oxidative, and anti-proliferative effects [14][15][16][17][18]. Baicalin (5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one-7-O-D-b-glucuronic acid) is a plant-derived flavonoid isolated from Scutellaria baicalensis Georgi.…”

Section: Introductionmentioning

confidence: 99%

Effect of Baicalin on Wound Healing in a Mouse Model of Pressure Ulcers

Kim

Ham

Jung

et al. 2022

IJMS

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One of the most frequent comorbidities that develop in chronically ill or immobilized patients is pressure ulcers, also known as bed sores. Despite ischemia-reperfusion (I/R)-induced skin lesion having been identified as a primary cause of pressure ulcers, wound management efforts have so far failed to significantly improve outcomes. Baicalin, or 5,6,7-trihydroxyflavone, is a type of flavonoid which has been shown to possess a variety of biological characteristics, including antioxidative and anti-inflammatory effects and protection of I/R injury. In vitro wound scratch assay was first used to assess the function of baicalin in wound healing. We established a mouse model of advanced stage pressure ulcers with repeated cycles of I/R pressure load. In this model, topically applied baicalin (100 mg/mL) induced a significant increase in the wound healing process measured by wound area. Histological examination of the pressure ulcer mouse model showed faster granulation tissue formation and re-epithelization in the baicalin-treated group. Next, baicalin downregulated pro-inflammatory cytokines (IL-6 and IL-1β), while upregulating the anti-inflammatory IL-10. Additionally, baicalin induced an increase in several growth factors (VEGF, FGF-2, PDGF-β, and CTGF), promoting the wound healing process. Our results suggest that baicalin could serve as a promising agent for the treatment of pressures ulcers.

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