Pd13-08 Shift Work Is Associated With Altered Semen Parameters in Infertile Men

Kohn, Taylor P.; Pastuszak, Alexander W.; Pickett, Stephen M.; Kohn, Jaden R.; Lipshultz, Larry I.

doi:10.1016/j.juro.2017.02.696

Cited by 6 publications

(6 citation statements)

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“…found that semen parameters were decreased against sleep quantity, sleep quality and difficulty sleeping in infertile men (Kohn et al, 2017). They also demonstrated that testosterone levels, sperm density and total motile sperm count were lower in infertile shift workers than infertile nonshift workers (p =.026, p =.012 and p =.019 respectively).…”

Section: Discussionmentioning

confidence: 93%

“…However, what is known about the reasons for this decline in semen quality is limited. When the recent studies are examined, it is seen that the effect of poor sleep on semen quality is one of the interesting and emphasised issues (Chen et al., 2020; Du et al., 2020; Hvidt et al., 2020; Jensen et al., 2013; Kohn et al., 2017). It is seen that parameters such as sleep time, long or short sleep duration, sleep quality are emphasised with respect to sleep.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic

et al. 2021

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We aimed to evaluate the effect of shift work on semen parameters together with the effect of sleep quality in men attending infertility clinic. The participants were divided into two groups as follows: 104 shift worker men (Group 1) and 116 nonshift worker men (Group 2). Groups were compared in terms of semen parameters, Depression Anxiety Stress Scale-21 (DASS-21), and Pittsburg Sleep Quality Index (PSQI) scores. A higher rate of oligozoospermia and poor sleep quality and a lower mean normal morphology percentage was observed in shift workers than nonshift workers (p = .006, .039 and .036 respectively). In addition, a positive correlation was seen between sleep duration and sperm concentration, while a negative correlation was found between sleep latency and total sperm count. Shift working together with high PSQI score was also a significant association with oligozoospermia when controlling for the other variables of age, total testosterone, DASS-21 stress score, smoking and varicocele (OR = 2.11, 95% CI 1.03-4.34 and OR = 1.18, 95% CI 1.01-1.39 respectively). In this study, infertile shift workers had a lower percentage of normal morphology and higher rates of oligozoospermia and poor sleep quality.Considering that shift workers have lower sleep quality, it seems that shift working negatively affects the circadian rhythm. K E Y W O R D S semen parameter, shift work, sleep quality 2 of 7 | DEMIRKOL Et aL.shift work can undermine sleep quality by interfering with the body's natural circadian rhythm. Likewise, it was shown in a study that shift work is an independent risk factor for poor sleep quality (McDowall et al., 2017). Furthermore, shift work has been related to several health outcomes, including metabolic disorders, cardiovascular disease, mood disorders, as well as male reproductive disorders (Bara & Arber, 2009;

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Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic

et al. 2021

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“…Those with a sleep score >50 (poor sleep) had a 29% reduction (95% CI: 2 to 48) in sperm concentration, 25% decline (95% CI: -4 to 46) in total sperm count, 0.9% lower (95% CI: -3.1 to 4.9) motile spermatozoa, and 1.6% fewer (95% CI: 0.3 to 3.0) morphologically normal spermatozoa compared to the control group (16, 85). Kohn et al also found an inverse Ushaped relationship between sleep quality and sperm quality; the total motile count for moderate sleep quality was 15.4 M sperm/ml greater than individuals without sleep difficulty and 4.72 M sperm/ml greater than those with severe sleep difficulty (p = 0.018) (60).…”

Section: Sleep Quality and Male Fertilitymentioning

confidence: 93%

“…Demirkol et al found that shift workers (n = 104) had a higher incidence of oligozoospermia (p = 0.006) and lower mean normal morphology (p = 0.036) than non-shift workers (n = 116), while shiftwork (OR = 2.11, 95% CI: 1.03 to 4.34) was independently related to oligozoospermia in multivariate analysis (29). Kohn et al claimed that shift workers had lower sperm density (p = 0.012), total motile count (p = 0.019), and testosterone levels (p = 0.026) than non-shift workers, whereas no difference was observed in sperm volume and motility or FSH and LH levels (60). El-Helaly et al explored the impact of occupational exposure on male fertility and found that shiftwork significantly increased the risk of infertility (OR = 3.60, 95% CI: 1.12 to 11.57) (61), which was consistent with findings of Irgens et al who reported reduced sperm quality among shift workers (OR = 1.46, 95% CI: 0.89 to 2.40) (61).…”

Section: Shiftwork and Male Fertilitymentioning

confidence: 99%

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The potential impacts of circadian rhythm disturbances on male fertility

Bai

Jiang³

et al. 2022

Front. Endocrinol.

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A circadian rhythm is an internalized timing system that synchronizes the cellular, behavioral, and physiological processes of organisms to the Earth’s rotation. Because all physiological activities occur at a specific time, circadian rhythm disturbances can lead to various pathological disorders and diseases. Growing evidence has shown that the circadian clock is tightly connected to male fertility, and circadian perturbations contribute to infertility. The night shiftwork, insufficient sleep, and poor sleep quality are common causes of circadian disturbances, and many studies have reported that they impair sperm quality and increase the risk of male infertility. However, research on the impacts of light, body temperature, and circadian/circannual rhythms is relatively lacking, although some correlations have been demonstrated. Moreover, as the index of sperm quality was diverse and study designs were non-uniform, the conclusions were temporarily inconsistent and underlying mechanisms remain unclear. A better understanding of whether and how circadian disturbances regulate male fertility will be meaningful, as more scientific work schedules and rational lifestyles might help improve infertility.

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The Effect of Shift Work on Urogenital Disease: a Systematic Review

et al. 2018

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Recent evidence supports associations between non-standard shift work and an increase in the frequency of prostate cancer and the severity of erectile dysfunction, lower urinary tract symptoms, and hypogonadal symptoms, as well as worsening of semen parameters and fertility. These associations are strengthened by the presence of shift work sleep disorder (SWSD) which affects up to 20% of shift workers. No studies have assessed the impact of shift work on the frequency or severity of nephrolithiasis, interstitial cystitis, pelvic pain, prostatitis, or urinary tract infections. Non-standard shift work has been associated with a variety of negative health outcomes and urologic complications, especially with concurrent shift work sleep disorder. Recognition of these elevated risks among shift workers can aid in more effective screening for urologic conditions.

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Pd13-08 Shift Work Is Associated With Altered Semen Parameters in Infertile Men

Cited by 6 publications

References 0 publications

Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic

Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic

The potential impacts of circadian rhythm disturbances on male fertility

The Effect of Shift Work on Urogenital Disease: a Systematic Review

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