Pd07-08 fibroblast Activation Protein-Specific Mri Provides Improved Tumour Mapping in an Orthotopic Model of Prostate Cancer Compared to Prostate Specific Membrane Antigen
Abstract:performed spatial transcriptomic profiling to elucidate the molecular differences between TZ and PZ PCa.METHODS: We identified three patients who underwent radical prostatectomy for PCa (one each with PZ only, TZ only, and both PZ and TZ tumors) and used the NanoString's Digital Spatial Profiling (DSP) platform to quantify whole transcriptomic gene expression data (17,128 genes) in multiple regions of interest (ROI) per patient (42 cancer and 8 normal samples). Four morphology markers to facilitate ROI selecti… Show more
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