Paulownia as a Medicinal Tree: Traditional Uses and Current Advances

Ting, He; Vaidya, Brajesh Nanda; Perry, Zachary D.; Parajuli, Prahlad; Joshee, Nirmal

doi:10.9734/ejmp/2016/25170

Cited by 63 publications

(30 citation statements)

References 44 publications

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“…Phenylethanoid glycosides have antioxidant, anti-inflammatory anticancer, hepatoprotective, immunostimulating, and antibacterial. Verabascoside and its several derivatives were isolated from bark and wood of P. tomentosa [ 2 , 3 , 4 ]. Paulownia has been shown to contain many bioactive ingredients, e.g., sesamin in the wood, ursolic acid in the leaves and catalpinoside in the bark.…”

Section: Introductionmentioning

confidence: 99%

“…Paulownia has been shown to contain many bioactive ingredients, e.g., sesamin in the wood, ursolic acid in the leaves and catalpinoside in the bark. Paulownia fruits are rich in, among others, alkaloids and flavonoids with antioxidant properties [ 3 ]. The flowers have been found to contain flavonoids such as apigenin, quercetin, apigenin-7- O -glucoside, quercetin-3- O -glucoside, 3-methoxyluteolin-7- O -glucoside, and tricin-7- O -glucopyranoside [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

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Comparative Phytochemical, Antioxidant, and Hemostatic Studies of Extract and Four Fractions from Paulownia Clone in Vitro 112 Leaves in Human Plasma

et al. 2020

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Background: The Paulownia Clone in Vitro 112, known as oxytree or oxygen tree, is a hybrid clone of the species Paulownia elongata and Paulownia fortunei (Paulowniaceae). The oxytree is a fast-growing hybrid cultivar that can adapt to wide variations in edaphic and climate conditions. In this work, Paulownia Clone in Vitro 112 leaves were separated into an extract and four fractions (A–D) differing in chemical content in order to investigate their chemical content using LC-MS analysis. The extract and fractions were also evaluated for their anticoagulant and antioxidant properties in a human plasma in vitro. Results: The Paulownia leaf extract contained mainly phenolic compounds (e.g., verbascoside), small amounts of iridoids (e.g., aucubin or 7-hydroxytometoside) and triterpenoids (e.g., maslinic acid) were also detected. Our results indicate that the extract and fractions have different effects on oxidative stress in human plasma treated with H2O2/Fe in vitro, which could be attributed to differences in their chemical content. For example, the extract and all the fractions, at the two highest concentrations of 10 and 50 µg/mL, significantly inhibited the plasma lipid peroxidation induced by H2O2/Fe. Fractions C and D, at all tested concentrations (1–50 µg/mL) were also found to protect plasma proteins against H2O2/Fe-induced carbonylation. The positive effects of fraction C and D were dependent on the dose. Conclusions: The extract and all four fractions, but particularly fractions C and D, which are rich in phenolic compounds, are novel sources of antioxidants, with an inhibitory effect on oxidative stress in human plasma in vitro. Additionally, the antioxidant potential of fraction D may be associated with triterpenoids.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparative Phytochemical, Antioxidant, and Hemostatic Studies of Extract and Four Fractions from Paulownia Clone in Vitro 112 Leaves in Human Plasma

et al. 2020

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“…elongata is a rapidly growing, sustainable source of hardwood that can be grown over a wide geographical footprint of the southern United States. This tree has a wide variety of potential uses including the production of honey [6], biocomposites [19][20][21], pencils [22], medicinal compounds [23], timber [24], and biomass [25]. Biochar made from P. elongata showed promise for athletic turf application [26] and other broader-based horticultural applications [11].…”

Section: Discussionmentioning

confidence: 99%

Silica-Milled Paulownia Biochar as Partial Replacement of Carbon Black Filler in Natural Rubber

Peterson

2019

J. Compos. Sci.

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Carbon black (CB) has been the dominant filler in the tire industry for decades. The demand for this petroleum byproduct is ever increasing, although petroleum markets can be volatile due to geopolitical issues. Finding sustainable, renewable substitutes for CB reduces the dependence on petroleum. Biochar is a renewable source of carbon that was studied as a potential CB replacement filler in styrene-butadiene rubber (SBR) composites, but little has been done in terms of natural rubber (NR). In this work, biochar made from fast-growing Paulownia elongata was co-milled with small amounts of silica in order to reduce the larger particle size typical with biochar respective to CB. The resulting silica-milled Paulownia biochar (PB) was then used to replace CB in natural rubber (NR) composites. By using this method to make natural rubber composites with 30% total filler, half of the CB was fully replaced with silica-milled biochar with very little loss (<6%) of tensile strength, and equal or better elongation and toughness compared to the 100% CB-filled control composite.

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“…Moreover, their leaves, flowers, fruits and root barks are also traditionally used as Chinese herbal folk medicines for the treatment of enteritis, tonsillitis, bronchitis, dysentery, etc. (He et al 2016). Phytochemical research has indicated that Paulownia plants contain quinones, lignans, triterpenes, phenylpropanoid glycosides, and flavonoids (Xing et al 2013;He et al 2016).…”

Section: Introductionmentioning

confidence: 99%

“…(He et al 2016). Phytochemical research has indicated that Paulownia plants contain quinones, lignans, triterpenes, phenylpropanoid glycosides, and flavonoids (Xing et al 2013;He et al 2016). However, Cgeranylated flavonoids, as the main constituents, have attracted much attention due to their structural variation and assorted biological properties.…”

Section: Introductionmentioning

confidence: 99%

Paulownia C-geranylated flavonoids: their structural variety, biological activity and application prospects

et al. 2019

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Paulownia species, especially their flowers and fruits, are traditionally used in Chinese herbal medicines for the treatment of infectious diseases. Cgeranylated flavonoids were found to be the major special metabolites in Paulownia flowers and fruits, and 76 C-geranylated flavonoids had been isolated and characterized thus far. Structural variations in Paulownia C-geranylated flavonoids are mainly due to the complicated structural modifications in their geranyl substituents. These natural compounds have attracted much attention because of their various biological activities, including antioxidation, antiinflammation, cytotoxic activity and various enzymatic inhibitions, etc. Among them, diplacone, a major Paulownia component, was considered to have promise for applications in medicine. This paper summarizes the information from current publications on Paulownia C-geranylated flavonoids, with a focus on their structural variety, key spectroscopic characteristics, biological activity with structureactivity relationships and application prospects. We hope that this paper will stimulate further investigations of Paulownia species and this kind of natural product.

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Paulownia as a Medicinal Tree: Traditional Uses and Current Advances

Cited by 63 publications

References 44 publications

Comparative Phytochemical, Antioxidant, and Hemostatic Studies of Extract and Four Fractions from Paulownia Clone in Vitro 112 Leaves in Human Plasma

Comparative Phytochemical, Antioxidant, and Hemostatic Studies of Extract and Four Fractions from Paulownia Clone in Vitro 112 Leaves in Human Plasma

Silica-Milled Paulownia Biochar as Partial Replacement of Carbon Black Filler in Natural Rubber

Paulownia C-geranylated flavonoids: their structural variety, biological activity and application prospects

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