Patterns of gastritis and the effect of eradicating Helicobacter pylori on gastro‐oesophageal reflux disease in Western patients with non‐ulcer dyspepsia

Abstract

SUMMARY Background

Effect of Helicobacter pylori Infection and Its Eradication on Reflux Esophagitis and Reflux Symptoms

“…H. pylori eradication does not cause refl ux esophagitis in Western patients with functional dyspepsia ( 41,42 ). In Japanese health examinees, however, development of refl ux esophagitis was more common in patients cured of H. pylori than in patients positive for H. pylori ( 43 ).…”

Utility of ancillary stains for Helicobacter pylori in near-normal gastric biopsies

“…The role of H. pylori in other illnesses, such as nonulcer dyspepsia, iron deficiency anemia, and gastroesophageal reflux disease is controversial, and the benefits of treatment are not clear [9][10][11][12]. Pathologists are often prompted by clinical colleagues to order ancillary stains for H. pylori detection, despite the absence of inflammatory background changes in mucosal biopsy samples on the assumption that patients with these disorders may benefit from H. pylori eradication therapy.…”

Gastric mucosal status in patients with reflux esophagitis

“…22,24 In this study; diffuse antral gastritis was more common than environmental metaplastic atrophic gastritis. Vakil et al, 25 reported that antrum gastritis is the most common pattern of gastritis seen in Western populations. This atrophic gastritis had significantly lower frequency of reflux esophagitis as compared with diffuse antral gastritis.…”