Patterns of acute inferior wall myocardial infarction caused by hyperkalemia

Pastor, Juan Antonio; Castellanos, Agustín; Moleiro, Federico; Myerburg, Robert J.

doi:10.1054/jelc.2001.22062

Cited by 22 publications

(18 citation statements)

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“…Review of 24 cases in the literature of pseudomyocardial infarction due to hyperkalemia revealed that an anterior-septal pseudo-infarct pattern is most common (19 cases; 79.2%) (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17). Three cases (12.5%) involved both anterior-septal and inferior distribution (18,19). An isolated inferior pattern and a single case of pseudo-anterior-lateral infarct also have been identified (13,20).…”

Section: Discussionmentioning

confidence: 99%

Pseudo-Myocardial Infarction in Diabetic Ketoacidosis with Hyperkalemia

Bellazzini

Meyer

2010

The Journal of Emergency Medicine

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Section: Discussionmentioning

confidence: 99%

Pseudo-Myocardial Infarction in Diabetic Ketoacidosis with Hyperkalemia

Bellazzini

Meyer

2010

The Journal of Emergency Medicine

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“…Em humanos, não foram encontrados, na literatura consultada, relatos de lesões como degeneração e necrose em células cardíacas associadas à hipercalemia, apenas foram descritas alterações no eletrocardiograma (ECG) (Chawla et al 1978, Pastor et al 2001.…”

Section: Introductionunclassified

Troponina C na detecção imuno-histoquímica de alterações regressivas precoces no miocárdio de ovinos naturalmente intoxicados por Amaranthus spinosus (Amaranthaceae)

et al. 2016

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ABSTRACT.-Costa S.Z.R., Peixoto P.V., Brust L.A.C., d' Avila M.S., Santos A.M., Driemeier D., Nogueira V. A. & França T.N. 2016. [Troponin C in the immunohistochemistry detection of early regressive changes in sheep myocardium naturally poisoned by Amaranthus spinosus (Amaranthaceae).] Troponina C na detecção imuno-histoquímica de alterações regressivas precoces no miocárdio de ovinos naturalmente intoxicados por Amaranthus spinosus (Amaranthaceae). Pesquisa Veterinária Brasileira 36(2):83-89. Curso de Pós-Graduação em Medicina Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, BR-465 Km 7, Seropédica, RJ 23890-000, Brazil. E-mail: samayzillmann@gmail.com Amaranthus spp. are nephrotoxic plants popularly known as "pigweed". In cases of poisoning by these plants, the main histopathological alteration is found in the kidneys as toxic tubular nephrosis; however, in some cases, there may be cardiac changes. ECG changes associated with hyperkalemia have been described in pigs poisoned by Amaranthus retroflexus. Degeneration and necrosis of myocytes have been described in pigs poisoned by A. caudatus and sheep poisoned by A. spinosus. There are doubts regarding cardiac changes, since in most cases they are incipient and don't exhibit inflammatory reaction, which can lead to misinterpretation. For this study, paraffin blocks with tissues from a poisoning outbreak by A. spinosus in southeastern Brazil were used. The objective of the study was to detect the presence of incipient regressive changes in the myocardium of sheep poisoned by A. spinosus using anti-troponin C antibody-based immunohistochemistry. Fragments of hearts from 8 adult sheep and 2 fetuses naturally poisoned by A. spinosus were used. In the immunohistochemistry evaluation of the 8 hearts from the adult sheep there were several groups of myocytes with significant decrease or absence of immunoreactivity for anti-troponin C antibody. In most cases, these same areas on Hematoxylin and Eosin (HE) staining exhibited changes that varied from mild cellular tumefaction to increased eosinophilia, as well as loss of striation, cell lysis and karyolysis, sometimes accompanied by inflammatory infiltrate. In four cases, it was possible to notice that several small groups of myocytes exhibited decreased immunoreactivity corresponding to cells with undetectable or very subtle alterations on HE staining. The hearts of both fetuses did not exhibit areas with loss or decreased immunoreactivity for the anti-troponin C antibody. The results of this immunohistochemical evaluation confirmed the presence of incipient regressive changes and confirmed the occurrence of well-established necrotic lesions in the myocardium of sheep poisoned by Amaranthus spinosus. There was correspondence between areas where immunostaining for troponin was absent and areas with the most marked lesions obser-1 Recebido em 24 de julho de 2015Aceito para publicação em 28 de novembro de 2015 Parte da Tese de Doutorado do primeiro autor.

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“…2,3 Additionally, approximately 3% of patients with suspected STEMI are found to have angiographically normal coronary arteries. 4 Electrolyte abnormalities including hyperkalemia [5][6][7] and hypercalcemia [7][8][9][10][11] may present with STsegment elevation and a pseudo-infarction pattern on the electrocardiogram (ECG). In patients presenting with suspected STEMI, the decision to proceed with invasive angiography must often be made before laboratory results are available.…”

Section: Introductionmentioning

confidence: 99%