Patterns in the prevalence of diabetes and incidence of diabetic complications in people with and without an intellectual disability in Dutch primary care: Insights from a population-based data-linkage study

Cuypers, Maarten; Leijssen, Martijn; Gijssel, E.J. Bakker-van; Pouls, Katrien P.M.; Naaldenberg, Jenneken; Leusink, Geraline L

doi:10.1016/j.pcd.2020.11.012

Cited by 13 publications

(9 citation statements)

References 32 publications

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“…This method for identifying individuals with ID in population data has been described in more detail elsewhere 27 and has been applied to other studies related to health and ID before. 21 , 28 , 29 All individuals without ID characterization were analyzed as members of the general population.…”

Section: Methodsmentioning

confidence: 99%

Cancer‐related mortality among people with intellectual disabilities: A nationwide population‐based cohort study

Cuypers¹,

Schalk²,

Boonman³

et al. 2021

Cancer

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BACKGROUND:Concerns have been raised about access to cancer screening and the timely receipt of cancer care for people with an intellectual disability (ID). However, knowledge about cancer mortality as a potential consequence of these disparities is still limited. This study, therefore, compared cancer-related mortality patterns between people with and without ID. METHODS: A historical cohort study (2015-2019) linked the Dutch adult population (approximately 12 million people with an ID prevalence of 1.45%) and mortality registries. Cancer-related mortality was identified by the underlying cause of death (according to the chapter on neoplasms in the International Classification of Diseases, Tenth Revision). Observed mortality and calculated age-and sex-standardized mortality ratios (SMRs) with 95% confidence intervals (CIs) were reported. RESULTS: There were 11,102 deaths in the ID population (21.7% cancer-related; n = 2408) and 730,405 deaths in the general population (31.2%; n = 228,120) available for analysis. Cancer was noted as the cause of death more often among people with ID in comparison with the general population (SMR, 1.48; 95% CI, 1.42-1.54), particularly in the young age groups. High-mortality cancers included cancers within the national screening program (SMRs,, digestive cancers (SMRs, 1.24-2.56), bladder cancer (SMR, 2.07; 95% CI, 1.61-2.54), and cancers of unknown primary (SMR, 2.48; 95% CI, 2.06-2.89). CONCLUSIONS: Cancer was reported as the cause of death approximately 1.5 times more often in people with ID compared with the general population. This mortality disparity may indicate adverse effects from inequalities in screening and cancer care experienced by people with ID.

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Section: Methodsmentioning

confidence: 99%

Cancer‐related mortality among people with intellectual disabilities: A nationwide population‐based cohort study

Cuypers¹,

Schalk²,

Boonman³

et al. 2021

Cancer

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“…People with ID of any aetiology had a significantly elevated risk of 16 diseases. Diabetes (undefined or both type I and II), epilepsy and asthma were consistently reported to be more prevalent [ 10 , 53 , 68 , 95 , 118 ]. Epilepsy had the highest effect size, ranging from 23.73 to 31.03.…”

Section: Resultsmentioning

confidence: 99%

“…It is important to maximise the representativeness of future study populations. Linkage of multiple administrative and clinical datasets, including multiple levels of healthcare and disability services, may be one solution [ 148 ], as illustrated in recent high-quality studies [ 40 , 118 ]. Data linkage studies should also capture disability severity to enhance the clinical utility of their results.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and incidence of physical health conditions in people with intellectual disability – a systematic review

et al. 2021

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Objective To synthesize evidence on the prevalence and incidence of physical health conditions in people with intellectual disability (ID). Methods We searched Medline, PsycInfo, and Embase for eligible studies and extracted the prevalence, incidence, and risk of physical health conditions in people with ID. Results Of 131 eligible studies, we synthesized results from 77 moderate- to high-quality studies, which was mainly limited to high-income countries. The highest prevalence estimates were observed for epilepsy, ear and eye disorders, cerebral palsy, obesity, osteoporosis, congenital heart defects, and thyroid disorders. Some conditions were more common in people with a genetic syndrome. Compared with the general population, many health conditions occur more frequently among people with ID, including asthma and diabetes, while some conditions such as non-congenital circulatory diseases and solid cancers occur at the same or lower rate. The latter associations may reflect under-detection. Conclusions People with ID have a health profile more complex than previously known. There is a pressing need for targeted, evidence-informed population health initiatives including preventative programs for this population.

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“…Complications secondary to diabetes, especially cardiological complications, were noted to be less than the general population. 40 Hospitalisations secondary to diabetes-related complications were noted to be three times higher than the general population. 41 A large multi-ethnic cohort study (the STOP diabetes crosssectional screening study) detected 1.3 percent of persons with ID to have diabetic status and 5.2 percent to have impaired glucose tolerance.…”

Section: Diabetesmentioning

confidence: 98%

Common Physical Health Issues in Persons with Intellectual Disability

Sriram¹

2022

SFP

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Persons with Intellectual Disabilities (ID) have a higher prevalence of physical health impairments leading to morbidities and premature deaths. The common conditions implicated are epilepsy, gastrointestinal concerns such as constipation and dyspepsia, sensory impairments, musculoskeletal issues, and thyroid disorders. Chronic diseases including hypertension, type 2 diabetes, obesity, and metabolic syndromes occur at an earlier age and nearly half of these conditions are detected only by screening. Annual health checks by primary care teams in the community are being implemented in many countries. Comprehensive health checks using standard questionnaires and preventative health check guidelines specially designed for persons with intellectual disabilities are of great help to primary care physicians in busy clinical settings. Addressing the concerns raised by healthcare professionals on the lack of knowledge and understanding of health needs of persons with ID can be easily addressed by appropriate training programmes. Eliminating communication barriers can be achieved by appropriate training programmes and implementing the use of easy-read materials. Reasonable adjustments must be implemented in practices to facilitate better health experiences for persons with ID and their caregivers.

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Patterns in the prevalence of diabetes and incidence of diabetic complications in people with and without an intellectual disability in Dutch primary care: Insights from a population-based data-linkage study

Cited by 13 publications

References 32 publications

Cancer‐related mortality among people with intellectual disabilities: A nationwide population‐based cohort study

Cancer‐related mortality among people with intellectual disabilities: A nationwide population‐based cohort study

Prevalence and incidence of physical health conditions in people with intellectual disability – a systematic review

Common Physical Health Issues in Persons with Intellectual Disability

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