Patterns in the incidence, mortality and survival of malignant pleural and peritoneal mesothelioma, New South Wales, 1972–2009

Abstract

Introduction: Malignant pleural mesothelioma (MPM) and malignant peritoneal mesothelioma (MPeM) are often grouped together in descriptive epidemiological analyses, resulting in limited understanding of epidemiological patterns for these tumour types. Methods:We studied patterns in the incidence, mortality and survival of people diagnosed with MPM (n=4,076) and MPeM (n=293) in New South Wales (NSW), Australia, 1972Australia, -2009. We also calculated 5-year relative survival for people diagnosed 1972-2006 followed up to 2007. We assessed patterns for each tumour type and histological subtype and, where possible, by combination of these categories.Results: Annual MPM cases steadily increased over time (n=208 in 2009). There was an increasing trend in the MPM age-standardised incidence rate from 1972 up to 1994. This rate increase has levelled off in the past 10 years. Since 1999, 11 cases of MPeM were diagnosed each year, on average. Five-year relative survival remained stable for MPM and MPeM. However, 5-year relative survival in 2002-2006 was substantially higher for people with MPM epithelioid histological subtype (11.7% .2%]) compared to all other non-epithelioid histological subtypes (6.9% [95%CI 5.0-9.1%]), a 70% difference. Survival was also greater for women with .4%]) compared to men (7.0% [95%CI 5.1-9.2%]).Interpretation: MPM incidence rates have stabilised since the mid-1990s, suggesting that maximum incidence levels have been reached. When more up-to-date data are available, survival estimates should be reanalysed to include people likely to benefit from the wide introduction of combination chemotherapy in 2007, including pemetrexed.

Malignant Peritoneal Mesothelioma: Patterns of Care and Survival in The Netherlands. A Population Based Study.

“…Therefore, most cases of MPM are not staged according to a uniform system, which generates heterogeneous outcomes between series. 9,[11][12][13] This study found that 20% of patients experienced distant metastases, which is considerably more than in studies published by Liu et al and Yan et al 14,20 Before 2009, the sites of metastases from MPM were not specifically reported in the Dutch National Cancer Registry. Analysis of the reported data during the period between 2009 and 2016 showed that metastases occurred in 23.4% of the cases.…”

“…Although an increasing percentage of patients receive anti-cancer therapy, the majority of The patient characteristics found in this study are comparable with those described in earlier reports. [9][10][11][12][13][14] Women with MPM live longer than men with MPM. It is sometimes suggested that the better survival among women is caused by a misdiagnosis of MPM because it has similarities to ovarian cancer.…”

Malignant Peritoneal Mesothelioma: Patterns of Care and Survival in the Netherlands: A Population-Based Study

“…Although efforts have been made to develop a staging system,20 to date, no standardized method has been implemented on a international level. Therefore, most cases of MPM are not staged according to a uniform system, which generates heterogeneous outcomes between series 9,11–13…”

Intraoperative Photodynamic Therapy for Peritoneal Mesothelioma

“…Это агрессивное заболевание четко коррелирует с воздействием асбеста. Исследования по мезотелиоме брюшины встречаются редко, поскольку 93-95% всех мезотелиом локализуются в плевральной полости [3,4].…”