Pattern of extra pulmonary tuberculosis among urban population with special reference to CBNAAT as a diagnostic tool: a retrospective study at a tertiary care hospital of Odisha, India

Rao, Chetana; Thakur, Bhaskar; Subhankar, Saswat; Dash, Debabrata

doi:10.18203/2320-6012.ijrms20184049

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…EPTB was more witnessed in male (54.6%) than female (45.4%). 25 Similar observations were made in the study by Ramaprakash et al, who documented 51.52% males and Mavila R et al, who reported 112 (59.9%) male as sufferers of extra-pulmonary TB. 26,27 CBNAAT results of EPTB specimen revealed higher diagnostic yield from lymph node aspirate and pus compared to no detection from pleural fluid, CSF and peritoneal fluids.…”

Section: Resultssupporting

confidence: 82%

Pattern of tuberculosis among tribal population of Central India with special reference to cartridge based nucleic acid amplification test as diagnostic tool: a descriptive study at tertiary care hospital

2019

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Background: Tuberculosis (TB) kills close to half a million Indians every year. Lack of reliable rapid diagnostic techniques for TB hampers timely diagnosis and leads to continued disease transmission, causing significant morbidity and mortality. The potential of newly recommended CBNAAT in TB and MDR-TB detection has been underutilized in our area due to lack of awareness regarding the same. Hence we utilized this rapid, logistically simplified test to study the pattern of tuberculosis among tribal population of Central India.Methods: Descriptive study of suspected TB patients in tertiary care centre from March 2016 to March 2019. Appropriate specimens from suspected TB patients were collected and subjected to CBNAAT and AFB smear to study the pattern of TB and Rifampicin- Resistant(RR) TB in our area.Results: CBNAAT detected overall 27% MTB cases; 27.72 % Pulmonary-TB cases as against smear positivity rate of 20.73% whereas 12.74% Extra-pulmonary-TB (EPTB) cases as against smear positivity rate of 1.59%.Overall 94.91% were RiF Sensitive( RS-TB) and 4.58% were RR-TB. Of the 57 (4.16%) HIV-TB coinfected cases; 96.49% were RS-TB and 5.26% were RR-TB. Co-infected patients have high incidence of EPTB(21.05%) involvement with RR-TB 3.50%. Among EPTB cases; lymph node aspirate and pus provided highest CBNAAT positive cases and almost 90.62% EPTB specimens were RS-TB .Conclusions: Availability of new diagnostic services has increased early identification of TB and RR-TB. Awareness among physicians regarding diagnostic utility of CBNAAT should be further increased as early identification of possible MDR cases is key to reducing community transmission and treatment initiation, particularly in high-burden, resource-limited settings.

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Section: Resultssupporting

confidence: 82%

Pattern of tuberculosis among tribal population of Central India with special reference to cartridge based nucleic acid amplification test as diagnostic tool: a descriptive study at tertiary care hospital

2019

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Utility of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of tuberculous lymphadenitis compared to GeneXpert in a tertiary health care center in Northern Odisha, India

Gouda¹,

Das²,

Dhangadamajhi

2021

Indian Journal of Tuberculosis

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A Retrospective Analysis of Extra Pulmonary Tuberculosis

Mathew

Irfan

Mynalli

et al. 2022

ijsr

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Tuberculosis has been one of the major public health concerns since many years now. Around 15-20% of TB cases are found to be extrapulmonary1. Diagnosis is challenging due to its pauci bacillary nature2. The objective of this study is to determine the pattern and sites of extra pulmonary tuberculosis in patients presenting to our tertiary hospital. Materials and Methods- This is a hospital based retrospective observational study. A total of 73 patients were included in the study. Study period was 1 year (Jan 2019 – Jan 2020). Data regarding the various samples, sites and various tests done – AFB, CBNAAT were collected. Both microbiologically or clinically diagnosed extrapulmonary tuberculosis were included. Records were obtained from the medical records maintained in the DOTS centre of our hospital. Results-Majority of the patients belonged to the age group of 21-40 years (42.5%) with male (61.6%) predominance. Most common extrapulmonary site was pleura (27.8%) and least common was endometrium (1.4%). 71.2% of the cases were clinically diagnosed and 28.8% were microbiologically conrmed. CBNAAT detected TB bacilli in 23.3% of the cases. Conclusion- In our study the most common site of extrapulmonary tuberculosis was pleura presenting as pleural effusion and in majority of them TB bacilli could not be detected.

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Pattern of extra pulmonary tuberculosis among urban population with special reference to CBNAAT as a diagnostic tool: a retrospective study at a tertiary care hospital of Odisha, India

Cited by 4 publications

References 11 publications

Pattern of tuberculosis among tribal population of Central India with special reference to cartridge based nucleic acid amplification test as diagnostic tool: a descriptive study at tertiary care hospital

Pattern of tuberculosis among tribal population of Central India with special reference to cartridge based nucleic acid amplification test as diagnostic tool: a descriptive study at tertiary care hospital

Utility of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of tuberculous lymphadenitis compared to GeneXpert in a tertiary health care center in Northern Odisha, India

A Retrospective Analysis of Extra Pulmonary Tuberculosis

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