Pattern of care in locally advanced breast cancer: Focus on local therapy

Sinacki, Marcin; Badzio, A.; Wełnicka-Jaśkiewicz, Marzena; Bogaerts, Jan; Piccart, Martine; Therasse, Patrick; Smith, Ian; Hatschek, Thomas; Jassem, Jacek

doi:10.1016/j.breast.2010.08.008

Cited by 20 publications

(13 citation statements)

References 51 publications

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“…Primary systemic therapy in inoperable LABC allows breast-conserving surgery in variable percentages depending on tumour/patient characteristics [43]. Mastectomy remains the only option before or after radiotherapy for those patients not amenable to breast conservation and for all patients with IBC [44].…”

Section: Inoperable Locally Advanced Inflammatory Breast Cancermentioning

confidence: 99%

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)

Cardoso¹,

et al. 2014

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Section: Inoperable Locally Advanced Inflammatory Breast Cancermentioning

confidence: 99%

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)

Cardoso¹,

et al. 2014

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“…Breast cancer (BC) is the most common cancer in women and approximately 20-25 % of the patientsdiagnosed with BC is locally advanced (Sinacki et al, 2011). Locally advanced disease includes a subset of patients with clinical stage IIB disease (T3N0) and patients with stage IIIA to IIIC disease.…”

Section: Introductionmentioning

confidence: 99%

The Neutrophil to Lymphocyte Ratio has a High Negative Predictive Value for Pathologic Complete Response in Locally Advanced Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Eryılmaz

Mutlu²,

Salim³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…There are regional differences in the incidence of LABC due to accessibility to medical services (12). Due to advancements in systemic therapy, the extent of surgical treatment required for LABC has decreased (13).…”

Section: Discussionmentioning

confidence: 99%

Application of a rhomboid flap for the coverage of defects after malignant breast tumor resection: A case report

et al. 2017

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Abstract. Resection for locally advanced breast cancer (LABC) or malignant phyllodes tumors may cause a large skin defect with bone exposure. Although skin grafts are frequently used to cover such defects, they can result in poor cosmetic outcomes and graft acceptance is dependent upon the condition of the recipient site. To overcome the limitations of skin grafts, various flaps have been developed to cover such defects. The present study used a rhomboid flap for the coverage of skin defects after mastectomy and breast-conservative surgery (BCS). A total of 11 patients with malignant breast cancer underwent reconstructive surgery using the rhomboid flap between September 2011 and December 2013 (mastectomy, 9 patients; BCS, 2 patients). Skin resection size, axillary lymph node dissection, bone exposure, length of surgery, wound complications and whether preoperative/postoperative adjuvant therapy was received were analyzed. The maximum size of skin defect covered with the rhomboid flap in the present study was 20x20 cm. There were no major wound complications and all patients underwent postoperative adjuvant therapy on schedule. During BCS, a portion of the flap was used for augmentation of the breast, in addition to coverage of the skin defect, which resulted in good cosmetic outcomes. The rhomboid flap can be quickly and easily fashioned, and it does not require any special instruments.

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Pattern of care in locally advanced breast cancer: Focus on local therapy

Abstract: The most frequent local therapy in LABC remains a combination of surgery and radiotherapy. Clinical and pathological characteristics influence the type of local treatment.

Cited by 20 publications

References 51 publications

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)

The Neutrophil to Lymphocyte Ratio has a High Negative Predictive Value for Pathologic Complete Response in Locally Advanced Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Application of a rhomboid flap for the coverage of defects after malignant breast tumor resection: A case report

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