Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project

Banerjee, Amitava; Taillandier, Sophie; Olesen, Jonas Bjerring; Lane, Deirdre A.; Lallemand, Bénédicte; Lip, Gregory Y.H.; Fauchier, Laurent

doi:10.1016/j.ijcard.2012.06.118

Cited by 71 publications

(66 citation statements)

References 26 publications

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“…These results differ from the Euro Observational Research Programme on Atrial Fibrillation (EORP-AF) where females had more non-ischemic HF and HF with preserved EF [6]. Similarly in Euro Heart Survey on Atrial Fibrillation females had more co-morbidities including HF with preserved EF [17]. Secondly, in our study, female patients had more often a permanent type of AF.…”

Section: Discussioncontrasting

confidence: 94%

“…It is likely that on follow-up some of the patients progressed to permanent type of AF. For example, in the Loire Valley AF Project, only permanent type of AF was associated with increased mortality [17]. Our data on mortality concerns only shortterm follow-up what is why the analysis of types is possible, because the percentage of patients who progressed to permanent type was low.…”

Section: Discussionmentioning

confidence: 88%

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Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

et al. 2015

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Background: Information on epidemiology of atrial fibrillation (AF) in Middle European 001). Patients with valvular AF had more often permanent AF (p < 0.004). Valvular AF patients were more often prescribed antithrombotic therapy (p = 0.001). The in-hospital mortality did not differ between patients with valvular and non-valvular AF (p = 0.3). In multivariate logistic regression, odds of in-hospital death were higher for patients > 75 years old (OR = 6.26, p = 0.001,) and with ejection fraction < 35% (OR = 5.25, p < 0.001, (Cardiol J 2015; 22, 3: 296-305)

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Section: Discussioncontrasting

confidence: 94%

Section: Discussionmentioning

confidence: 88%

Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

et al. 2015

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“…[4][5][6][7] In accordance with the results from these studies, current guidelines worldwide recommend the use of oral anticoagulant (OAC) for the prevention of thromboembolism, irrespective of the type of AF. [8][9][10] However, more recent studies have reported that the patients with PAF had a lower rate of stroke/systemic embolism (SE).…”

mentioning

confidence: 83%

“…Previous randomized clinical studies 4,5 and observational registry studies 6,7 have suggested that patients with PAF have a risk of thromboembolic events similar to that in patients with SAF.…”

Section: Controversy About the Type Of Af As A Stroke Riskmentioning

confidence: 99%

Incidence of Stroke or Systemic Embolism in Paroxysmal Versus Sustained Atrial Fibrillation

Takabayashi

Hamatani

Yamashita

et al. 2015

Stroke

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106

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A trial fibrillation (AF) is the most common cardiac arrhythmia in developed countries and increases the risks for stroke, heart failure, and death.1 Until 2 decades ago, the incidence and risk factors for stroke were less well characterized in patients with paroxysmal AF (PAF) when compared with those with persistent or permanent AF.2,3 Since then, several studies have reported that patients with PAF have a risk of thromboembolic events that was similar to that in persistent or permanent AF. [4][5][6][7] In accordance with the results from these studies, current guidelines worldwide recommend the use of oral anticoagulant (OAC) for the prevention of thromboembolism, irrespective of the type of AF. [8][9][10] However, more recent studies have reported that the patients with PAF had a lower rate of stroke/systemic embolism (SE). 11-13Also, patients with PAF are less likely to receive OAC therapy in the real-world clinical practice.6,14 However, limited data on stroke risk associated with PAF are evident in Asian populations with PAF because most studies were epidemiological studies on Western populations or selected clinical trial cohorts.Background and Purpose-There is controversy on the relationship of the type of atrial fibrillation (AF) to stroke.Although several studies show that patients with paroxysmal AF (PAF) have a stroke risk similar to those with persistent or permanent AF, recent studies suggest that PAF is associated with a lower rate of stroke. Limited data on stroke risk associated with PAF are evident in Asian populations. Methods-The Registry Study of Atrial Fibrillation Patients in Fushimi-ku (Fushimi AF Registry) is a community-basedsurvey of patients with AF in Fushimi-ku, Kyoto, Japan. Patients were categorized into 2 types of AF: PAF or sustained (persistent or permanent) AF. We compared clinical events between PAF (n=1588) and sustained AF (n=1716). Results-Patients with PAF were younger, had less comorbidities, and received oral anticoagulants (OAC) less commonly.A lower risk of stroke/systemic embolism during follow-up period in the patients with PAF was consistently observed (non-OAC users: hazard ratio, 0.45; 95% confidence intervals, 0.27-0.75; P<0.01 and OAC users: hazard ratio, 0.59; 95% confidence interval, 0.35-0.93; P=0.03). The composite end point of stroke/systemic embolism/all-cause mortality was also lower in PAF, whether among OAC users (hazard ratio, 0.77; 95% confidence interval, 0.59-0.99; P=0.046) or non-OAC users (hazard ratio, 0.59; 95% confidence interval, 0.46-0.75; P<0.01). On multivariate analysis, PAF was an independent predictor of lower stroke/systemic embolism risk. Conclusions-In this large cohort of Japanese patients with AF, PAF was independently associated with lower incidence of stroke/systemic embolism than sustained AF. This may aid decision making for anticoagulation, especially in those patients with AF with few stroke risk factors. Clinical Trial Registration

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“…Uzyskano pewne dowody wskazujące na to, że nasilenie AF może wpływać na ryzyko udaru mózgu [44,124,164] i mogłoby modyfikować odpowiedź na leczenie w celu kontroli rytmu serca [76,165]. Przemawiające za tym dowody są jednak słabe.…”

Section: Elektrokardiograficzne Wykrywanieunclassified

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof

Benussi

Kotecha³

et al. 2016

Kardiol Pol

2,384

4,206

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Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project

Cited by 71 publications

References 26 publications

Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

Management of patients with valvular and non-valvular atrial fibrillation in Poland: Results from Reference Cardiology University Center

Incidence of Stroke or Systemic Embolism in Paroxysmal Versus Sustained Atrial Fibrillation

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

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