Patients assisted at the Department of Medicine of a pediatric hospital at the beginning of the COVID-19 pandemic in Buenos Aires, Argentina

Cairoli, Héctor; Raiden, Silvina; Chiolo, María J.; Lalla, Sandra Di; Ferrero, Fernando; Colaboradores,

doi:10.5546/aap.2020.eng.423

Cited by 4 publications

(7 citation statements)

References 7 publications

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“…In the present review, only 11 of the 20 studies described the clinical type of COVID-19 (13)(14)(15)19,(22)(23)(24)(27)(28)(29)(30), eight of which described asymptomatic cases (13)(14)(15)22,24,27,28,30), and six described severe or critical cases (13)(14)(15)23,27,28). These findings showed that, although important, information about the clinical type and outcome is scarce in the literature and needs more attention to clarify the real impact of COVID-19 on children.…”

Section: Discussionmentioning

confidence: 72%

“…The main outcome of the evaluated cases was cure. Supplementary Table S1 shows the data collected from the studies included in this review (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”

Section: Resultsmentioning

confidence: 99%

“…China was the country that most described the symptoms of COVID-19 in children, totaling six articles included in this review (18,19,22,27,28,30). On the other hand, when considering the diversity of countries on the same continent, the American continent stands out (12)(13)(14)16,24,26,29,31). This finding highlights the magnitude of COVID-19, first detected in Asia and which, as it spread around the world, led to new studies in other regions that also investigated specificities, such as symptoms in children (1,5,(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”

Section: Discussionmentioning

confidence: 99%

“…The various manifestations of the respiratory system were detailed in 18 studies (12)(13)(14)(15)(16)18,19,(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31), with cough being the most frequent and addressed in a general way in two other studies (17,20). Dyspnea was reported in 60% of the studies, and should be taken as a warning sign for SARS.…”

Section: Discussionmentioning

confidence: 99%

“…Several symptoms related to the gastrointestinal system were observed (12)(13)(14)(15)(16)(17)(18)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31), although four studies considered the manifestations without subdivision, that is, considering the entire system (15,24,26,30).…”

Section: Discussionmentioning

confidence: 99%

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Symptoms of COVID-19 in children

Melo¹,

Neta²,

Neto³

et al. 2022

Braz J Med Biol Res

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Section: Discussionmentioning

confidence: 72%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Symptoms of COVID-19 in children

Melo¹,

Neta²,

Neto³

et al. 2022

Braz J Med Biol Res

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Epidemiology and clinical evolution of non-multisystem inflammatory syndrome (MIS-C) dermatological lesions in pediatric patients affected by SARS-CoV-2 infection: A systematic review of the literature

et al. 2022

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COVID-19 can present with a range of skin manifestations, some of which specific of the pediatric age. The aim of this systematic literature review was to determine the type, prevalence, time of onset, and evolution of cutaneous manifestations associated with COVID-19 in newborns, children, and adolescents, after excluding multisystem inflammatory syndrome in children (MIS-C). PubMed, Tripdatabase, ClinicalTrials, and Cochrane Library databases were searched using an ad hoc string for case reports/series and observational studies, published between December 2019 and February 2022. Study quality was assessed using the STROBE and CARE tools. Seventy-three (49 case reports/series and 24 studies) out of 26,545 identified articles were included in the analysis. Dermatological lesions were highly heterogeneous for clinical presentation, time of onset, and association with other COVID-19 manifestations. Overall, they mainly affected the acral portions, and typically presented a favorable outcome. Pseudo-chilblains were the most common. Conclusions : Mucocutaneous manifestations could be the only/predominant and early manifestation of COVID-19 that could precede other more severe manifestations by days or weeks. Therefore, physicians of all disciplines should be familiar with them. What is Known: • A variety of cutaneous manifestations have been reported in association with COVID-19. • Urticaria, maculopapular, or vesicular rashes can occur at any age, while chilblains and erythema multiforme are more common in children and young patients. What is New: • Skin lesions related to SARS-CoV-2 infection often show a peculiar acral distribution. • Mucocutaneous lesions of various type may be the only/predominant manifestation of COVID-19; they could present in paucisymptomatic and severely ill patients and occur at different stages of the disease. Supplementary Information The online version contains supplementary material available at 10.1007/s00431-022-04585-7.

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