Patient-specific computer modeling of blood flow in cerebral arteries with aneurysm and stent

Takizawa, Kenji; Schjodt, Kathleen; Puntel, Anthony; Kostov, Nikolay; Tezduyar, Tayfun E.

doi:10.1007/s00466-012-0760-4

Cited by 95 publications

(35 citation statements)

References 117 publications

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“…In general, CFD methods allow flow patterns, particle residence times, and shear stress distributions to be obtained at a great level of detail and simulation parameters to be easily varied. Increasingly complex models of arterial segments have been generated and studied [5][6][7][22][23][24], leading to a deeper understanding of the influence of geometry, flow waveforms, viscosity, and wall distensibility on flow and shear stress patterns. Figure 8 shows the flow rate throughout the models during the cardiac cycle before and after stenting.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Numerical Simulation of Coronary Artery Stenosis Before and After Stenting

Gao

2015

J. Med. Biol. Eng.

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This study simulates the effect of stenting in an image-based coronary model. Three-dimensional models of the coronary artery were created from computed tomography images of a coronary artery stenosis patient before and after stent implantation, and a realistic aortocoronary differential pressure was imposed at the inlet of the computational vessels. The results show that the stent increased the flow rate several fold compared to that for the stenosis artery model, and that the hemodynamic values returned to near normal levels in the coronary artery model fitted with a stent. The results confirm that stenting significantly improves the hemodynamics of the artery.

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Section: Resultsmentioning

confidence: 99%

“…Computational cardiovascular fluid mechanics is one of the most popular research areas in computational mechanics [5][6][7]. The geometric configuration of vascular segments greatly affects the resulting flow patterns.…”

Section: Introductionmentioning

confidence: 99%

Numerical Simulation of Coronary Artery Stenosis Before and After Stenting

Gao

2015

J. Med. Biol. Eng.

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“…Some examples of these applications are animal swimming and flight [13,22,[60][61][62][63][64][65][66], flag flapping [28], spacecraft parachutes [67][68][69][70][71][72][73][74][75][76][77], cardiovascular fluid mechanics [78][79][80][81][82], wind-turbine aerodynamics [83][84][85][86], and non-Newtonian flow [87].…”

Section: Methodsmentioning

confidence: 99%

A numerical study of linear and nonlinear kinematic models in fish swimming with the DSD/SST method

Tian

2014

Comput Mech

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Flow over two fish (modeled by two flexible plates) in tandem arrangement is investigated by solving the incompressible Navier-Stokes equations numerically with the DSD/SST method to understand the differences between the geometrically linear and nonlinear models. In the simulation, the motions of the plates are reconstructed from a vertically flowing soap film tunnel experiment with linear and nonlinear kinematic models. Based on the simulations, the drag, lift, power consumption, vorticity and pressure fields are discussed in detail. It is found that the linear and nonlinear models are able to reasonably predict the forces and power consumption of a single plate in flow. Moreover, if multiple plates are considered, these two models yield totally different results, which implies that the nonlinear model should be used. The results presented in this work provide a guideline for future studies in fish swimming.

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“…The computations reported in 2012 were for detailed analysis of parachute FSI [85][86][87][88], arterial FSI [89,90], flow in aneurysms blocked with stent [91], wind-turbine aerodynamics [92], and bioinspired flapping-wing aerodynamics [18,93,94]. The detailed parachute studies, all for the Orion spacecraft parachutes, were for different designs of the suspension lines and overinflation control line, reefed parachute stages, different trial canopy design configurations, different payload models, 2-parachute clusters, FSIbased dynamical analysis of single parachutes and parachute clusters, disreefing of single parachutes and parachute clusters, parachutes with modified geometric porosity, and Stage 2 shape determination for the modified-geometric-porosity parachute.…”

Section: Years 2011-2018mentioning

confidence: 99%

Space–time computations in practical engineering applications: a summary of the 25-year history

Tezduyar

Takizawa

2018

Comput Mech

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In an article published online in July 2018 it was stated that the algorithm proposed in the article is "enabling practical implementation of the space-time FEM for engineering applications." In fact, space-time computations in practical engineering applications were already enabled in 1993. We summarize the computations that have taken place since then. These computations started with finite element discretization and are now also with isogeometric discretization. They were all in 3D space and were all carried out on parallel computers. For quarter of a century, these computations brought solution to many classes of complex problems ranging from Orion spacecraft parachutes to wind turbines, from patient-specific cerebral aneurysms to heart valves, from thermo-fluid analysis of ground vehicles and tires to turbocharger turbines and exhaust manifolds.

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Patient-specific computer modeling of blood flow in cerebral arteries with aneurysm and stent

Cited by 95 publications

References 117 publications

Numerical Simulation of Coronary Artery Stenosis Before and After Stenting

Numerical Simulation of Coronary Artery Stenosis Before and After Stenting

A numerical study of linear and nonlinear kinematic models in fish swimming with the DSD/SST method

Space–time computations in practical engineering applications: a summary of the 25-year history

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