Patient Quality of Life and Symptoms after Surgical Treatment for Endometriosis

Comptour, Aurélie; Chauvet, Pauline; Canis, Michel; Grémeau, Anne-Sophie; Pouly, Jean-Luc; Rabischong, B.; Pereira, Bruno; Bourdel, Nicolas

doi:10.1016/j.jmig.2018.08.005

Cited by 32 publications

(35 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We were not able to establish any differences in symptom relief regarding the rASRM stage, which also corresponds to the results of Vercellini et al [33]. Comptour et al [43] also demonstrated that laparoscopic endometriosis lesions resection irrespective of the rASRM stage has a positive, minimum three-year effect on both symptoms (lower abdominal pain, dyspareunia) and the quality of life.…”

Section: Stage-related Surgical Procedures and Postoperative Rate Of supporting

confidence: 84%

Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis.

Schippert

Witte

Bartels

et al. 2020

Preprint

View full text Add to dashboard Cite

Background Endometriosis can be associated with considerable pain and sterility. After surgical excision of moderate or severe endometriosis the recurrence rates amount to 50%. The objective of this retrospective study was to evaluate the recurrence and pregnancy rates following surgical resection of endometriosis stage III/IV. Methods 456 patients who underwent stage III/IV endometriosis surgery between 2004 and 2014 were sent a questionnaire relating to postoperative medical treatment, pregnancies, relief of symptoms and recurrence. Data and responses of 206 patients (45.2%) were analyzed. The statistical analysis was performed with the statistical software ´R`. Statistical significance was given if the p-value was less than 0.05. The study was approved by the local Ethics Committee of Hannover Medical School. Results 66.5% (N=137) of patients were established with stage III, 33.5% (N=69) with stage IV. Average age was 37 years (17-59). 63.1% (N=130) of surgeries were performed by laparoscopy with an average duration of 81 minutes, 21.8% (N=45; 189 minutes) by laparotomy and 15% (N=31; 202 minutes) by conversion. Complete resection of endometriosis was achieved in 90.8% (N=187). After surgery, 48.5% (N=100) of the women did not receive hormonal treatment, main reason was the desire for children in 53%. Complete or partial relief in complaints was achieved in 93.2% (N=192). Rate of recurrence was 21.8% (N=45). The association between incomplete resection and recurrence was on the threshold of significance (p=0.1). After surgery, 65.8% (79/120) of patients who wished to have children got pregnant. There is a statistically significant association between postoperative pregnancy rate and age <35 (p<0.002) and laparoscopic surgical access (p<0.01). Conclusion We assess the high percentage of complete or partial reduction of symptoms of 93.2%, the high postoperative pregnancy rate of 65.8% and the low rate of recurrence of 21.8% compared to international literature to be very encouraging for women suffering from moderate and severe endometriosis. Though laparoscopy is considered as ´gold standard` of endometriosis surgery, laparotomy still may be indicated in cases of extended endometriosis especially to preserve reproductive function.

show abstract

Section: Stage-related Surgical Procedures and Postoperative Rate Of supporting

confidence: 84%

Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis.

Schippert

Witte

Bartels

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Thereby, research indicates a link between decreased pain intensity and increased QoL. 46,47 However, a medical symptom-focused therapy to reduce pain symptoms might not be sufficient to ameliorate SQoL in women with endometriosis. Barbara et al 39 reviewed the existing literature on the effect of surgical and pharmacological treatment on female sexual dysfunction and found that even though improvement can be achieved, this treatment might not be a definitive solution.…”

Section: Clinical Applicability and Implicationsmentioning

confidence: 99%

Endometriosis and Sexual Quality of Life

et al. 2020

View full text Add to dashboard Cite

Introduction: Endometriosis is a benign gynecological disease with a high disease burden and significant, multifaceted impact on health-related quality of life (HRQoL) and sexual quality of life (SQoL). Aim: To explore which patient-and disease-specific characteristics were independently associated with SQoL. Methods: A literature search was carried out to identify characteristics with an evidence-based or hypothesized effect on SQoL. Subsequently, data on HRQoL in women with endometriosis (n ¼ 224), collected between 2013 and 2018 in a prospective longitudinal Dutch cohort study performed in 7 referral centers, were used to perform a cross-sectional cohort study. Data were collected using an online self-administered survey including the validated Endometriosis Health Profile-30. Inclusion criteria were recently diagnosed endometriosis patients or newly referred patients with a clinical diagnosis of endometriosis. Patients were excluded in case of incomplete answers on the SQoL questions. Univariate analyses and multiple linear regression analyses were performed. Outcomes: SQoL, measured by the 5-item "sexual intercourse" dimension score of the modular Endometriosis Health Profile-30 questionnaire, was the primary outcome with scores ranging from 0 to 100 (0 indicating the best and 100 indicating the worst health status). Results: Based on a literature search, 29 characteristics potentially associated with SQoL were selected from the survey and included in the analyses. In total, 192 women (mean age 36 years) met the inclusion criteria. The majority of women (86.5%) had had intercourse in the period before completing the survey and the study population showed a mean SQoL score of 47.5 ± 29.6, indicating moderate SQoL. Worse SQoL was independently associated with dyspareunia (P < .001), worse HRQoL (P ¼ .001), severity of dysmenorrhea (P ¼ .017), and unemployed work status (P ¼ .022). Conclusion: In a cohort of women with endometriosis, worse SQoL was significantly and independently associated with the presence of dyspareunia, more severe dysmenorrhea, worse HRQoL, and unemployed work status. van

show abstract

“…Many studies have shown the efficacy of laparoscopic surgery for patients with endometriosis in reducing painful symptoms and improving quality of life (QoL) in the short term [ 1 , 2 , 3 , 4 , 5 , 6 ] and some of them in the long-term [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. We previously analyzed the evolution of pain (dysmenorrhea, chronic pelvic pain, dyspareunia) and quality of life in this cohort over 3 years of follow-up, specifically focusing on the impact of surgical treatment of endometriosis [ 8 ]. We reported a global improvement in all reported symptoms and all QoL scores (physical and mental components) as early as six months after surgery.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Evolution of Quality of Life and Symptoms Following Surgical Treatment for Endometriosis: Different Trajectories for Which Patients?

Lambert

Chauvet

Figuier

et al. 2020

JCM

Self Cite

View full text Add to dashboard Cite

Many studies have shown a global efficacy of laparoscopic surgery for patients with endometriosis in reducing painful symptoms and improving quality of life (QoL) in the short and long-term. The aim of this study was to analyze the different trajectories of long-term evolution in QoL and symptoms following surgical treatment for endometriosis, and to identify corresponding patient profiles. This prospective and multicenter cohort study concerned 962 patients who underwent laparoscopic treatment for endometriosis. QoL was evaluated using the Short Form (SF)-36 questionnaire and intensity of pain was reported using a visual analog scale prior to surgery and at 6, 12, 18, 24 and 36 months after surgery. Distinctive trajectories of pain and QoL evolution were identified using group-based trajectory modeling, an approach which gathers individuals into meaningful subgroups with statistically similar trajectories. Pelvic symptom trajectories (models of the evolution of dysmenorrhea, dyspareunia and chronic pelvic pain intensity over years) correspond to (1) patients with no pain or pain no longer after surgery, (2) patients with the biggest improvement in pain and (3) patients with continued severe pain after surgery. Our study reveals clear trajectories for the progression of symptoms and QoL after surgery that correspond to clusters of patients. This information may serve to complete information obtained from epidemiological methods currently used in selecting patients eligible for surgery.

show abstract

Patient Quality of Life and Symptoms after Surgical Treatment for Endometriosis

Cited by 32 publications

References 37 publications

Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis.

Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis.

Endometriosis and Sexual Quality of Life

Long-Term Evolution of Quality of Life and Symptoms Following Surgical Treatment for Endometriosis: Different Trajectories for Which Patients?

Contact Info

Product

Resources

About