Patient‐controlled analgesia with morphine and droperidol following caesarean section under spinal anaesthesia

Abstract

The addition of droperidol 10 mg to morphine 60 mg for PCA following caesarean section under spinal anaesthesia reduces the incidence of nausea and emesis, but may result in drowsiness, limiting the usefulness of the technique.

Droperidol Analgesia for Opioid-Tolerant Patients

“…More severe akathisia and dystonia may also require beta-blockers and benzodiazepines (86). Sedation is another adverse effect of droperidol and is likely a result of its aforementioned anticholinergic and mixed GABAergic properties (87). This may actually be advantageous when droperidol is used for procedural sedation or agitation.…”

Preoperative droperidol improved postoperative pain relief in patients undergoing rotator-cuff repair during general anesthesia using intravenous morphine

“…10 The addition of droperidol (PCA) morphine consumption. 3,4 Droperidol is reported to be effective as an antiemetic in doses of 5 to 70 g/kg. 8,11-14 Pandit et al 8 showed that 10 to 20 g/kg IV droperidol reduced PONV in patients undergoing outpatient laparoscopy with general anesthesia.…”

“…Previous clinical studies reported that epidural droperidol augmented an analgesic effect induced by epidural morphine, 1,2 and reduced patient-controlled analgesia (PCA) morphine consumption. 3,4 Moreover, another study has reported that droperidol itself shows an analgesic effect. 5 Nonetheless, this point remains controversial.…”

Evaluation of the Effective Drugs for the Prevention of Nausea and Vomiting Induced by Morphine Used for Postoperative Pain: A Quantitative Systematic Review

“…Evaluation by Jadad's scoring system, operation (setting), number of subjects, dosing regimen of morphine, dosing regimen of the test drug, number of patients who developed nausea and/or vomiting, and eŠec-tiveness are shown in this table. The test drug was droperidol in 11 studies, 7,8,12,[16][17][18][19][20][21] metoclopramide in 5 studies, 9,10,16,21) dexamethasone in 6 studies, [22][23][24] propofol in 4 studies, [25][26][27][28] and ondansetron in 5 studies. 9,12,15,22) The results of testing the lack of homogeneity the results of studies for each of the four test drugs are shown.…”