Pathophysiology of pelvic organ prolapse and stress urinary incontinence

A Rare Case of Pregnancy Complicated by Uterine Prolapse and Cervical Fibroid

“…Whereas, acute onset prolapse developing during pregnancy is more common, usually reported in the third trimester [8]. The etiology in the latter is presumed to be due to frail pelvic support, caused by repeated trauma to the pelvic floor or congenital connective tissue disorder [9]. Besides that high serum level of cortisol and progesterone during pregnancy softens and stretches the pelvic musculature and weakens the pelvic support leading to prolapse [10].…”