Pathophysiological Study of Sensitive Skin

Buhé,; K, Vié; Guéré, Christelle; Natalizio, Audrey; Lhéritier, C.; C, Le Gall-Ianotto; Huet, F.; Talagas, Matthieu; Lebonvallet, Nicolas; Marcorelles, Pascale; Jl, Carré; Miséry, Laurent

doi:10.2340/00015555-2235

Cited by 94 publications

(101 citation statements)

References 40 publications

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“…Indeed, histological observations have indicated that epidermal nerve fibres are present at higher densities in the skin of patients with itchy psoriasis (Nakamura et al , 2003; Taneda et al , 2011), lichenified atopic skin (Urashima and Mihara, 1998), photodamaged skin (Toyoda et al , 2005) and in a mouse model of xerosis (Tominaga et al , 2007), than in healthy individuals. On the other hand, IENFD have been shown to be reduced in conditions such as sensitive skin (Buhé et al , 2016), prurigo nodularis (Schuhknecht et al , 2011), and in a case report of grafted skin (Zeidler et al , 2016). It could be interesting to see if these changes in skin innervation can lead to pain of neuropathic characteristics.…”

Section: Discussionmentioning

confidence: 99%

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Bischhoffshausen

Ivulic

Alvarez

et al. 2017

Brain

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Section: Discussionmentioning

confidence: 99%

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Bischhoffshausen

Ivulic

Alvarez

et al. 2017

Brain

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“…A recent study has shown that the pathophysiology of skin sensitivity resembles that of neuropathic pruritus within the context of small fiber neuropathy, and that environmental factors may alter skin innervation 17. Reactive skin can appear normal or accompanied by erythema, can affect all body locations, particularly the face, and may worsen in the presence of a simultaneous dermatosis 16…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of fragile skin: Internet-based surveys in Mexico and Russia

Ocampo‐Candiani

Мурашкин

Zkik

et al. 2017

CCID

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BackgroundFragile skin is a poorly understood skin condition, particularly in the general adult population. There are currently limited epidemiological data on the prevalence of fragile skin in adults. The objectives of this study were to assess the prevalence of perceived fragile skin across different skin types in representative samples of the general adult populations in Mexico and Russia, and to identify skin characteristics associated with perceived fragile skin.MethodsTwo identical cross-sectional surveys, using a short online self-administered questionnaire, were conducted on samples of recruited individuals that were representative of the general Mexican and Russian populations. Participants responded to questions about fragile skin, with the main question being “In your opinion, do you have fragile skin (ie, skin less resistant and reacting quickly to external aggressions)?”. The survey also covered questions relating to skin appearance, skin symptoms, skin disease, dermatological procedures, and living environment and climate.ResultsOverall, 1,210 individuals in Mexico (N=606) and Russia (N=604) completed the online survey. Fragile skin was perceived in 50.0% and 45.9% of participants in Mexico and Russia, respectively. The principal skin appearance characteristics reported by individuals with perceived fragile skin were thin, easily wrinkled, and transparent; the main skin symptoms were dryness, redness, and/or itching (≥50% of individuals in Mexico), and dryness, tightness, and/or redness (>60% of individuals in Russia). Individuals with perceived fragile skin had experienced skin disease and/or undergone a dermatological procedure in the past 12 months, and they reported being exposed to stress (>80% of individuals in both surveys).ConclusionA substantial proportion of the general adult population of Mexico and Russia perceived that they had fragile skin, regardless of their skin type; fragile skin was perceived more frequently in women. These findings should assist dermatologists to extend their understanding and management of individuals with perceived fragile skin.

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“…The neuropathic origin of sensitive skin may be a result of degeneration of intraepidermal nerve fibers. 39 …”

Section: Skincare: Current State Of Playmentioning

confidence: 99%

Skincare Bootcamp: The Evolving Role of Skincare

Rodan¹,

Fields²,

Majewski³

et al. 2016

Plastic and Reconstructive Surgery - Global Open

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Background:Although cosmetic procedures have a significant impact on certain aspects of aging, such as deep, wrinkling, sagging, and volume loss, they fail to address the overall quality of the skin.Methods:Daily skincare routines potentially can have a significant long-term impact on the overall quality of a person’s complexion.Results:By expanding our product knowledge, we can help our patients individualize their at-home skincare routine using effective products and ingredients designed to address their specific skin concern and support the professional care we deliver.Conclusions:Here, we discuss the types of products and ingredients suitable for the most common dermatologic concerns, from wrinkling to skin sensitivity, acne to sun damage.

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Pathophysiological Study of Sensitive Skin

Cited by 94 publications

References 40 publications

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy

Epidemiology of fragile skin: Internet-based surveys in Mexico and Russia

Skincare Bootcamp: The Evolving Role of Skincare

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