Pathology Quiz Case

Congenital Neuroglial Heterotopia in a Neonatal Harbor Seal (Phoca vitulina richardsi ) with Evidence of Recent Exposure to Polycyclic Aromatic Hydrocarbons

“…Other terms used synonymously in the literature include glial choristoma (a mass of normal cells in an ectopic location), neuroglial hamartoma (abnormal growth of tissue that would normally occur at that site), heterotopic brain tissue, accessory brain, and nasal glioma; all but the term choristoma should be considered distinct lesions (Al-Nafussi et al, 1990;Harris et al, 1994;Roy and Gungor, 2002;Oya et al, 2005). Neuroglial heterotopia consists of mature neuroectodermal tissue including astrocytes and glial fibers embedded in a fibrovascular stroma (Ide et al, 1997), and may include other cellular components such as neurons, choroid plexus, and ependyma (Madjidi and Couly, 1993).…”