Pathology of Germ Cell Tumors

Zaloudek, Charles

doi:10.1007/978-1-4419-9751-7_13

Cited by 8 publications

(15 citation statements)

References 205 publications

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“…However, YST can be difficult to diagnose pathologically because they exhibit a wide variety of histologic patterns and multiple patterns are typically present in an individual tumor. The review of pathology in our patients showed that the two most common patterns were reticular pattern (also called microcystic pattern) and the endodermal sinus pattern, in agreement with the pathological literature (18). The reticular growth pattern of tumor cells formed microcystic or glandular structures, which contributed to the cystic or necrotic changes seen on the CT images (19).…”

Section: Discussionsupporting

confidence: 90%

“…In this study, there was an obviously uneven distribution of mixed YSTs with an adult: children ratio of 7:1, in accordance with the literature reports. Presence of any admixed malignant GCT component in the primary will make the efficacy of treatment become indefinite (18,21). It suggests that this mixed malignant tissue may continue to grow even as the tumor marker normalizes after chemotherapy (22).…”

Section: Discussionmentioning

confidence: 99%

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Radiological–pathological correlation of yolk sac tumor in 20 patients

Zheng

Lin

et al. 2014

Acta Radiol

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Radiological–pathological correlation of yolk sac tumor in 20 patients

Zheng

Lin

et al. 2014

Acta Radiol

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“…Ependymal rosettes should not be mistaken for the primitive rosettes seen in an immature teratoma. The cells lining ependymal rosettes have ample cytoplasm, the nuclei form only one or two layers, and mitotic figures are not present (14). In this case, foci of ependymal cells forming tubules and vague rosettes were also seen.…”

Section: Discussionmentioning

confidence: 77%

Congenital mature cystic teratoma of the lateral neck presenting as cystic hygroma: a rare case report with literature review

Win¹,

Razy²,

Hamid³

et al. 2014

TJPATH

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Teratoma of the neck is a rare extra-gonadal teratoma. Although it can be seen in adult, most of the cases present in fetal life or early childhood. Grading and classification of teratoma is important for management and prognosis. Decision making between mature and immature teratoma is sometime challenging if it is not composed of extensive unusual neuroectodermal tissue component. We reported a rare case of huge congenital mature cystic teratoma composted of various neuroectodermal tissues in an 8-month-old boy; it was located at the lateral neck and mimicked congenital cystic hygroma. A literature review was done to grade and classify the tumour.

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“…In general, the resection should be done completely with clear margin from cell tumors. [ 15 ] This margin issue is related to the possibility of recurrence of the tumor after resection although it is debatable.…”

Section: Discussionmentioning

confidence: 99%

Extragonadal yolk sac tumor following congenital buccal mature cystic teratoma

Rahadiani

Krisnuhoni

Stephanie

et al. 2019

J Oral Maxillofac Pathol

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Yolk sac tumor (YST) and teratoma both categorized as germ cell tumor (GCT). YST shows preferential differentiation toward yolk sac structures, while teratoma consists of tissues that originate from at least two embryonic germinal layers. Extragonadal location of YST is rare, whereas extragonadal teratoma is majority presented in nasopharynx area. Mature teratoma tends to be benign although some malignant transformation can occur. Recurrence of teratoma was reported mostly in the case of immature teratoma. YST occurrence after removal of mature teratoma is never reported. It is extremely rare for a second GCT to occur at the same site and with a different histological type. We herein report a case of a female infant presented with YST following a congenital buccal mature teratoma.

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Pathology of Germ Cell Tumors

Cited by 8 publications

References 205 publications

Radiological–pathological correlation of yolk sac tumor in 20 patients

Radiological–pathological correlation of yolk sac tumor in 20 patients

Congenital mature cystic teratoma of the lateral neck presenting as cystic hygroma: a rare case report with literature review

Extragonadal yolk sac tumor following congenital buccal mature cystic teratoma

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