Pathological Case of the Month

Kakkar, Nandita; Vasishta, R. K.; Anand, H. K.

doi:10.1001/archpedi.153.2.203

Cited by 13 publications

(14 citation statements)

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“…[4] Review of the literature reveals that synovial lipomatosis commonly affects adults. [5] In the present study the lesions predominantly occurred in older age groups and the median age was found to be 50 years, with 50% of the cases occurring after 50 years. In a series studied by Hallel et al, the age group ranged from 39 to 66 years.…”

Section: Discussionsupporting

confidence: 48%

“…Causes that have been implicated include, trauma, inflammation, rheumatism, and developmental and neoplastic processes. [5,8] Three cases in the present study occurred in patients having features of osteoarthritis. This change in the synovium possibly represents a protective and adaptive response to the longstanding injury of the articular cartilage.…”

Section: Discussionmentioning

confidence: 80%

“…[3,9,10] On clinical examination the differential diagnosis of synovial lipomatosis includes synovial lipoma, synovial chondromatosis, pigmented villonodular synovitis, synovial hemangioma, and rheumatoid arthritis. [5,8] It needs to be differentiated from other lesions affecting the synovium, as the treatment modalities differ. Magnetic resonance imaging exhibits the fatty nature of the lesion, with signal intensities similar to subcutaneous fat and it demonstrates a frond-like appearance.…”

Section: Discussionmentioning

confidence: 99%

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Pathology of Synovial Lipomatosis and its Clinical Significance

et al. 2011

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Background:Synovial lipomatosis is a rare disorder of the synovium, commonly affecting the knee joint, resulting in joint pain, swelling, and effusion. The etiology of this condition still remains unclear.Aim:This was a study done to evaluate the disease process in synovial lipomatosis, with respect to the clinical parameters and pathological features.Materials and Methods:Case files of synovial lipomatosis diagnosed on histopathology between 2007 and 2009 were perused, to study the case history, and tissue sections were reviewed for the histomorphological changes.Results:Eight cases of synovial lipomatosis were diagnosed on histopathology from year 2007 to 2009, of which one occurred in the wrist joint and the rest were localized to the knee joint. Age ranged from one year to seventy-three years, with a male preponderance. Pain and swelling were major complaints. Three had a significant past history, one occurring post-trauma, one following chikungunya, and another with septic arthritis. Three of the cases had osteoarthritis. Body mass index was elevated in four cases and one case had protein energy malnutrition. On histopathological examination, all the cases showed villous proliferation of the synovium, with focal and diffuse infiltration by mature adipocytes. Four cases showed focal hyperplasia of the lining epithelium and five cases revealed variable fibrosis.Conclusion:Synovial lipomatosis may mimic tumorous, lesion-like synovial lipoma or hemangioma and its distinct histomorphology helps in distinguishing it from these lesions. It possibly represents a secondary phenomenon following the degenerative process of articular disease of the joints.

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Section: Discussionsupporting

confidence: 48%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

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Pathology of Synovial Lipomatosis and its Clinical Significance

et al. 2011

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“…This entity often displays a frond‐like appearance of hypertrophied synovium referred to by the word “arborescens.” Although lipoma is a misnomer as there is no focal mass. Synovial lipomatosis has been suggested as a more proper descriptor of this diffuse fatty proliferation of the synovium (3).…”

mentioning

confidence: 99%

“…Although lipoma is a misnomer as there is no focal mass. Synovial lipomatosis has been suggested as a more proper descriptor of this diffuse fatty proliferation of the synovium (3).…”

mentioning

confidence: 99%

Lipoma arborescens of the peroneal tendon sheath

Moukaddam

Smitaman

Haims

2010

Magnetic Resonance Imaging

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Lipoma arborescens or synovial lipomatosis is a rare disorder characterized by mature fat infiltration of hypertrophic synovial villi, most frequently affecting the suprapatellar pouch of the knee. Involvement of the synovial tendon sheath is extremely rare with only a few reported cases in the literature. We present a case of lipoma arborescens involving the peroneal and flexor tendons sheaths of the ankle, review the few reported cases to date, and discuss MR imaging features of this rare entity.

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Synovial lipomatosis of the stifle joint in a dog

Orekhova

Schwarz

2021

Vet Record Case Reports

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Synovial lipomatosis has been described as a rare disease of the synovial membrane in humans. This report represents a synovial lipomatosis case of the left stifle joint in a dog, diagnosed by MRI and validated by histopathologic examination. Synovial lipomatosis can be difficult to recognise due to the absence of specific clinical features, especially in view of its similarity to other disorders with the benign or malignant origin in the synovial membrane. Therefore, the validation of this pathology could be essential in directing patient management. The aim of this report was to describe approaches required for the identification of synovial lipomatosis, such as clinical signs, diagnostic imaging characteristics and histological pattern, that have not been published previously in veterinary medicine.

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Pathological Case of the Month

Cited by 13 publications

References 0 publications

Pathology of Synovial Lipomatosis and its Clinical Significance

Pathology of Synovial Lipomatosis and its Clinical Significance

Lipoma arborescens of the peroneal tendon sheath

Synovial lipomatosis of the stifle joint in a dog

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