Pathological analysis of intracranial space-occupying lesions in 1000 cases including children

Histopathological Study of Tumors of Central Nervous System

“…The frequency was higher in developed countries than in developing countries. 2 3 The number of cases of brain tumor is not exactly known. The reason being the lack of complete registration of newly diagnosed cases with local cancer registries.…”

Solitary Pontine Tuberculoma.

“…Amongintracranial tuberculoma, brainstem tuberculoma is rare and it accounts for 2.5-8% of all intracranial tuberculoma in large series studies (1,2,8). Tuberculoma is formed as a result of hematogenous dissemination of Mycobacterium tuberculosis.…”

“…Therefore, CNStuberculoma tends to occur in the region of higher blood supply such as frontal or parietal lobe of the cerebrum. Most cases of pontine tuberculoma accompany supratentorial or meningeal lesions, and solitary lesion in the pons is rare (4,8). CNStuberculoma usually demonstrates the following features on MRI (3,6,9,10).…”

Intraventricular Tuberculoma. Case Report.

“…Ventricular involvement in the tuberculous process occurs as choroid plexus inflammation characterized by a covering of gelatinous exudates, ependymitis, and asymmetric hydrocephalus secondary to intraventricular adhesions or septae formation. 1,2,4,5,12) Tubercles (Rich foci) have been found within the choroid plexus, but well-developed intraventricular tuberculoma are extremely rare. Four cases of large intraventricular tuberculoma were found in children.…”

“…The incidence of intracranial tuberculomas was 30% of all identified cases of brain tumors before the advent of antituberculous chemotherapy in India in 1950, and still constitute a major health hazard, accounting for 4% of all intracranial space-occupying lesions. 1,4,5) In the developed countries, the incidence of intracranial tuberculoma is 0.15% to 0.18%, but it is more prevalent among the immigrants from the developing world. 8) Tuberculomas are usually located in the cerebellum and cerebral hemispheres, particularly in the frontoparietal region and basal ganglia, and rarely in the corpus callosum, quadrigeminal cistern, cerebellopontine angle, and retroorbital and suprasellar region.…”