Pathologic Study of Hypertensive Heart

Abstract

The pathologic findings of hypertensive hearts a r e represented by myocardial hypertrophy, especially those of the left ventricles, but hypertension without cardiac hypertrophy is not rare. The influence of hypertension is manifested not only as cardiac hypertrophy, but also as acceleration of coronary atherosclerosis.The present report is on some of the results of cardiac measurings, concerning hypertensive and non-hypertensive cases in Part I, and of the study on correlations between hypertension and coronary atherosclerosis in Part 11.The term "hypertensive" is used when the blood pressure had been maintained over 150mmHg in systolic, and 90mmHg in diastolic for a definite time, and had been diagnosed "hypertensive" by some doctor.The cases with organic cardiovascular diseases such as valvular lesions, pericarditis, congenital malformation and aortic aneurysms were excluded. Part 1 Measuring of the hearts MATERIALS The materials used for cardiac measuring were 117 hearts over 10 years of age, collected from autopsy cases at the Kurume University and Beppu National Hospital in Kyushu, Japan, from March 1960 to August 1963. Sixty cases were non-hypertensive (39 males and 21 females), and the remaining 57 were hypertensive (40 males and 17 females).

The impact of helical flow on coronary atherosclerotic plaque development

“…Furthermore, the results of this study serve to quantitatively explain for the first time the irregular helical-shaped distribution of fatty and fibrous plaques in coronary artery reported by previous ex vivo studies [29][30][31][32], and hinted at by the WT patterns shown for the representative case in Fig. 2, where the high WT region seems to follow a helical distribution.…”