Pathobiological features of breast tumours in the State of Kuwait: a comprehensive analysis

Saleh, F M; Abdeen, Suad

doi:10.1016/s1359-6349(08)71860-3

Cited by 8 publications

(18 citation statements)

References 27 publications

(35 reference statements)

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“…The proportional increase in ER and PR positivity with age was more marked for ER than for PR whereas some other studies have reported PR positivity with age was more marked than ER [3]. Further, Saleh and Abdeen [23] reported increased positivity of ER with age while PR positivity did not have any significant variation. A previous Western study also showed similar results, though other studies showed no correlation between age and Her2/neu expression [14,24].…”

Section: Discussionmentioning

confidence: 85%

Study of Hormone Receptors and Epidermal Growth Factor Expression in Invasive Breast Cancers in a Cohort of Western India

Dodiya¹,

Patel²,

Patel³

et al. 2013

Ind J Clin Biochem

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The objective of study was to evaluate and correlate the pathological characteristics of breast cancer patients with estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2/neu) detected by immunohistochemistry and/or fluorescent in situ hybridization method. We have conducted 2 year study of 204 cases of breast cancer at HCG-Medisurge Hospitals, Ahmedabad from 2009 to 2011. Significant correlation was found in ER and PR expression whereas no correlation was found in hormonal receptors and Her2/neu expression. ER and PR positivity increased with advancing age in breast carcinoma patients while not affecting Her2/neu expression. The expression of hormone receptors were higher in infiltrating lobular carcinoma and infiltrating duct carcinoma subtypes of breast carcinoma as compared to other subtypes such medullary and in situ carcinoma. High-grade carcinoma patients were predominantly ER/PR negative and Her2/neu positive as compared to lower grade breast carcinoma whereas high-stage carcinoma patients were ER/PR positive and Her2/neu positive as compared to lower stage breast carcinoma.

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Section: Discussionmentioning

confidence: 85%

Study of Hormone Receptors and Epidermal Growth Factor Expression in Invasive Breast Cancers in a Cohort of Western India

Dodiya¹,

Patel²,

Patel³

et al. 2013

Ind J Clin Biochem

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“…Estrogen and progesterone positive (ER+/PR+) tumors represented 51% of breast cancer cases among Indian women and 48% of cases among Mainland Chinese women (Ghosh et al, 2011;Wang et al, 2012b). In contrast, estrogen negative cancer was predominant among Kuwaiti women (69%) (Saleh and Abdeen, 2007).…”

Section: Discussionmentioning

confidence: 99%

Differences in Incidence, Mortality and Survival of Breast Cancer by Regions and Countries in Asia and Contributing Factors

Kim¹,

Yoo

Goodman

2015

Asian Pacific Journal of Cancer Prevention

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“…Similarly, in the study by Farid Saleh et al 18 the most common histologic subtype was infiltrating ductal carcinoma, NOS type (98%) and 2% of invasive papillary carcinoma.…”

Section: Discussionmentioning

confidence: 69%

“…None of the other types showed HER-2 positivity. Similarly, 90.9% and 71.7% of infiltrating duct carcinoma (NOS type) were positive for HER2/neu in the studies done by Naeem et al (2008) 21 and Saleh F et al 18 (2007).…”

Section: Discussionmentioning

confidence: 78%

A Study of Expression of Her2/Neu in Carcinoma Breast With Reference to Clinicopathological Features and Prognostic Index

R¹,

K²

2016

jemds

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BACKGROUNDCarcinoma of breast has clinical heterogeneity with high morbidity and mortality. Determination of prognostic factors is important in improving the overall survival in breast cancer patients. HER2/neu is one of the powerful predictors of poor prognosis. Thus, a study of HER2/neu expression estimated by immunohistochemistry in breast cancer is the need of the hour. This study investigates correlations between the presence of HER2/neu and various clinicopathological prognostic parameters in primary breast carcinomas. 1. Study of the HER2/neu status in breast carcinomas in the study sample. 2. To find the association of HER2/neu status with clinicopathological prognostic parameters in breast carcinomas in the study sample. 3. To find the association of HER2/neu status with lymph node status.

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Pathobiological features of breast tumours in the State of Kuwait: a comprehensive analysis

Cited by 8 publications

References 27 publications

Study of Hormone Receptors and Epidermal Growth Factor Expression in Invasive Breast Cancers in a Cohort of Western India

Study of Hormone Receptors and Epidermal Growth Factor Expression in Invasive Breast Cancers in a Cohort of Western India

Differences in Incidence, Mortality and Survival of Breast Cancer by Regions and Countries in Asia and Contributing Factors

A Study of Expression of Her2/Neu in Carcinoma Breast With Reference to Clinicopathological Features and Prognostic Index

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