Paternity and Hormone Levels After Unilateral Cryptorchidism: Association With Pretreatment Testicular Location

Lee, Peter A.; Coughlin, Michael T.; Bellinger, Mark F.

doi:10.1016/s0022-5347(05)67087-5

Cited by 54 publications

(21 citation statements)

References 13 publications

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“…Subanalysis of abdominal and extra-abdominal testes by Abrahams et al confirmed no significant differences in size [11]. Lee et al also showed that preoperative testicular location of the undescended testis in men with previous unilateral cryptorchidism was not a major determinant of fertility, according to paternity, sperm count, or hormone levels [12]. In our study, there was no difference in testicular volume among each position of the undescended testis.…”

Section: Discussionsupporting

confidence: 56%

Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism

et al. 2008

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Section: Discussionsupporting

confidence: 56%

Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism

et al. 2008

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“…They concluded, somewhat controversially, that the lack of significant variations in testicular size implies early orchidopexy at age younger than 2 years was not essential. Lee et al found no correlation between the position of the cryptorchid, preoperatively, and adult sperm density and paternity [46,47]. This was based on their findings of 90% paternity in their cohort of 320 previously repaired unilateral cryptorchid patients and sperm analysis from 21 patients with intra-abdominal/internal ring testis.…”

Section: Testicular Volumementioning

confidence: 96%

Orchidopexy and its impact on fertility

2007

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We critically analysed the factors known to influence the fertility potential after orchidopexy in children. A comprehensive literature review of all publications in the English language listed in Medline using the words cryptorchidism, undescended testis, orchidopexy, fertility, semen analysis and surgery from 1970 to 2005. In unilateral ectopic, canalicular and emergent testes, as long as the surgery is carried out in early childhood, fertility outcome is good (>90%). The majority of the bilateral abdominal testes are infertile. While unilateral abdominal testes and unilateral absent or vanishing testes have favourable fertility potential, quantification has proven difficult. Despite multiple studies, fertility in crypt orchid tests is still an uncertain issue. Hormonal treatment in conjunction with early surgical correction has not been fully explored. We recommend orchidopexy soon after 6-7 months of age, corrected for term, to maximise the future fertility potential.

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“…Monat zu behandeln [4,6]. Dieses Alter wird aus mehreren Gründen emp fohlen: Die Wahrscheinlichkeit eines spontanen Deszensus nach den ersten 3-4 Monaten ist gering, eine Reduzierung der Anzahl von Gonozyten scheint bereits in diesem Alter zu beginnen, und die The rapie (hormonell und/oder chi rurgisch) ist heutzutage relativ erfolgreich und risi koarm [4,6,7].…”

Section: Grundlagenunclassified

Hodenhochstand und Infertilität unter besonderer Berücksichtigung der interdisziplinären Leitlinie

Mathers

Degener

Roth

2011

Urologe

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Cryptorchidism is the most common genital disorder in boys. Early-born boys are affected in up to one third of the cases, while about 2-5% of full-term newborns suffer from at least one undescended testicle. As a result of short-term endogenous testosterone secretion after birth the prevalence decreases to 1-2% after 3 months. According to most studies, watchful waiting after 6 months is not justified because after this time spontaneous testicular descent only very rarely occurs. Even though the effects of testicular development and fertility in undescended testis have been extensively examined, the only fact that remains certain is that approximately 90% of untreated men with bilateral cryptorchidism develop azoospermia. The remaining scenarios of cryptorchidism (unilateral, ectopic, inguinal, treated or not treated) exhibit unpredictable fertility and likelihood of fatherhood.

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Paternity and Hormone Levels After Unilateral Cryptorchidism: Association With Pretreatment Testicular Location

Abstract: Preoperative testicular location in men with previous unilateral cryptorchidism is not a major determinant of fertility according to paternity, sperm count or hormone levels.

Cited by 54 publications

References 13 publications

Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism

Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism

Orchidopexy and its impact on fertility

Hodenhochstand und Infertilität unter besonderer Berücksichtigung der interdisziplinären Leitlinie

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