Patent research in salmonellosis prevention

Santhi, Lakshmi P.; Sunkoji, Sampath; Siddiram, Siddeshwar; Sanghai, Sujata S.

doi:10.1016/j.foodres.2011.11.006

Cited by 6 publications

(2 citation statements)

References 13 publications

(12 reference statements)

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“…Salmonella is a facultative intracellular enteric pathogen that infects both humans and animals ( Andino and Hanning, 2015 ). Gastrointestinal diseases of infectious origin caused by the ingestion of food contaminated by this pathogen constitute a significant public health problem in the world ( Santhi et al, 2012 ). It is estimated that 535,000 cases of invasive non-typhoid Salmonella disease occurred in 2017, causing 77,500 deaths ( Stanaway et al, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Salmonella enterica Optimizes Metabolism After Addition of Acyl-Homoserine Lactone Under Anaerobic Conditions

et al. 2020

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Acyl-homoserine lactones (AHLs) are quorum sensing (QS) signaling molecules that mediate cell-to-cell communication in Gram-negative bacteria. Salmonella does not produce AHL, however, it can recognize AHLs produced by other species through SdiA protein modulating important cellular functions. In this work, the influence of the N -dodecanoyl-DL-homoserine lactone (C12-HSL) on glucose consumption, metabolic profile, and gene expression of Salmonella throughout the cultivation time in Tryptic Soy Broth (TSB) under anaerobic conditions was evaluated. Analysis of the supernatant culture in high-performance liquid chromatography (HPLC) revealed lower glucose uptake after 4 and 6 h of the addition of C12-HSL. Gas chromatography-mass spectrometry (GC-MS) based analysis of the intracellular metabolites revealed C12-HSL perturbation in the abundance levels of metabolites related to the metabolic pathways of glycerolipids, purines, amino acids, and aminoacyl-tRNA biosynthesis. The real-time quantitative PCR (RT-qPCR) indicated that Salmonella increase expression of genes associated with nucleoside degradation and quantification of metabolites supported the induction of pentose phosphate pathway to ensure growth under lower glucose consumption. The obtained data suggest an important role of C12-HSL in the optimization of metabolism at a situation of high population densities.

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Section: Introductionmentioning

confidence: 99%

Salmonella enterica Optimizes Metabolism After Addition of Acyl-Homoserine Lactone Under Anaerobic Conditions

et al. 2020

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“…In this context, Santhi, Sunkoji, Siddiram, and Sanghai (2012) reviewed the Salmonellarelated patenting activities between 1999 and 2010, determined the most active patent fillers, the origin of the patents, patent focus and trends of salmonellosis prevention through patenting activities.…”

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confidence: 99%

Introduction to the Special Issue: Salmonella in foods: Evolution, strategies and challenges

Sant’Ana

2012

Food Research International

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Furanone and phytol influence metabolic phenotypes regulated by acyl-homoserine lactone in Salmonella

et al. 2022

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Patent research in salmonellosis prevention

Cited by 6 publications

References 13 publications

Salmonella enterica Optimizes Metabolism After Addition of Acyl-Homoserine Lactone Under Anaerobic Conditions

Salmonella enterica Optimizes Metabolism After Addition of Acyl-Homoserine Lactone Under Anaerobic Conditions

Introduction to the Special Issue: Salmonella in foods: Evolution, strategies and challenges

Furanone and phytol influence metabolic phenotypes regulated by acyl-homoserine lactone in Salmonella

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