Patch testing in discoid eczema

Fleming, Colin; Parry, E. J.; Forsyth, A.; Kemmett, D

doi:10.1111/j.1600-0536.1997.tb00214.x

Cited by 35 publications

(17 citation statements)

References 7 publications

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“…In our study, only 6% of patients had atopy, as defined by the presence of atopic eczema, hay fever, asthma, or conjunctivitis. This finding is consistent with the majority of studies, which suggest that atopy is not associated with discoid eczema (5–8). In addition, nummular eczema patients have significantly lower IgE levels than atopic eczema patients (11), suggesting no common role for IgE in the two conditions.…”

Section: Discussionsupporting

confidence: 93%

“…It is a clinical entity characterized by a single, non‐specific morphological feature, namely, circular or oval plaques of eczema with clearly demarcated edges (4). It often overlaps with other clinical types of eczema but has no specific histological features (5). Despite this, it is readily recognised by dermatologists, and the term continues to be commonly used.…”

Section: Introductionmentioning

confidence: 99%

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Patch Testing in Discoid Eczema

Khurana

Jain

Aggarwal

et al. 2002

The Journal of Dermatology

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Fifty patients of both sexes with clinically suspected discoid eczema were patch tested with the Indian Standard Patch Test Battery approved by the Contact and Occupational Dermatosis Forum of India (CODFI). Most of these patients were young adults between 20 and 39 years old, with a mean age of 36 years. The mean duration of symptoms was 21/2 years. The occupational profiles of the patients included farmers (24%), housewives (18%), students (14%), housewives engaged in farming (12%), shopkeepers (10%), and laborers (8%). The miscellaneous group, including technicians, drivers, cable operators, office workers, and computer operators, accounted for the remaining 14%. The common clinical patterns of presentation of discoid eczema included hands and feet (44%), hands and forearms' (30%), legs and feet (12%) and trunk and limbs (12%). Patch test analysis of these patients revealed that, out of the 50 subjects tested, 28 (56%) reacted to one or more allergens. Potassium dichromate was the most common allergen (20%), followed by nickel (16%), cobalt chloride, and fragrance (12% each) in decreasing order of frequency. Hence, it may be concluded that patch testing should be considered for all patients with severe or persistent discoid eczema because allergic contact dermatitis may be relatively common in such patients and the avoidance of offending allergens may be of substantial benefit to the patients.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Patch Testing in Discoid Eczema

Khurana

Jain

Aggarwal

et al. 2002

The Journal of Dermatology

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“…In a series of 4825 patients, patch-tested by 10 dermatologists in 7 European countries, 100 subjects (2.1%) had nummular dermatitis, and 17% of these had relevant positive reactions. 23 Others have reported variable incidence of contact allergy in nummular eczema, ranging from 30.1%, 24 40.6%, 27 50%, 25,26 up to 77.9%. 39 Regardless of such variability from one case series to another, likely a bias from different cohorts numbers, the above data suggest that contact allergy is common in persistent discoid eczema.…”

Section: Contact Allergymentioning

confidence: 97%

Nummular Eczema and Contact Allergy

Bonamonte¹,

Foti²,

Vestita³

et al. 2012

Dermatitis

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“…bacterial infection, role of atopy, allergic contact dermatitis, varicose veins and lower leg edema, dietary factors, environmental factors, systemically administered drugs etc. [3][4][5][6][7][8] Contact sensitization to different allergens has been proposed as one of the causative factor. There are few studies on incidence of allergic contact dermatitis in patients with relapsing nummular eczema from India, and perhaps none from a hilly region of the subcontinent.…”

Section: Introductionmentioning

confidence: 99%

“…6 The most common allergens implicated were rubber chemicals, formaldehyde, neomycin, chrome and nickel.…”

mentioning

confidence: 99%

Role of contact allergens in chronicity and relapses of nummular eczema

Rattan

Tegta

Shanker³

et al. 2017

Int J Res Dermatol

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Background: Endogenous eczemas are often complicated by exogenous factors like environment and contact allergens. Nummular eczema, a variant of endogenous eczema is no exception to this. Our study aimed at investigating the incidence of allergic contact dermatitis and finding offending agent responsible for chronicity or relapsing course of nummular eczema in patients from a hilly region with cold and dry environmental conditions.Methods: Forty patients of nummular eczema with a mean age of 39.1±19 years were patch tested with the Indian Standard Patch Test Series. Positive reactions were graded as per recommendations of International contact dermatitis research group.Results: Twenty one out of forty patch tested patients showed positive reactions. The most common allergens were found to be: fragrance mix in seven (17.5%) patients, nickel in five (12.5%) patients, PPD in three (7.5%) patients and gentamicin in two (5%) patients. Sensitivity to thiuram mix, black rubber mix, P. tert. butylphenol formaldehyde, neomycin, benzocaine and chinoform was observed in one patient each (2.5% each). Conclusions: Patients of nummular eczema of a hilly region are at a significant risk of developing allergic contact dermatitis owing to xerosis due to dry environmental conditions. This results in chronic nature of their disease. Patch testing should be considered in such patients and avoidance of offending allergens can improve their quality of life.

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Patch testing in discoid eczema

Cited by 35 publications

References 7 publications

Patch Testing in Discoid Eczema

Patch Testing in Discoid Eczema

Nummular Eczema and Contact Allergy

Role of contact allergens in chronicity and relapses of nummular eczema

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