Passive transfer in light urticaria

Solar urticaria

“…5 Thereafter, reports of action spectra and phototesting become common. In 1942, Rajka 6 showed that the urticarial response could be passively transferred by intradermal injection of the serum of an affected solar urticaria patient into a normal subject. As described in the Pathogenesis section below, over the last century, several key studies have sought to elucidate the cause(s) of solar urticaria.…”

Solar urticaria: the annoying photodermatosis

“…That solar urticaria is due to an antigen–antibody reaction and that the antigen is produced in the skin after solar irradiation have been known for half a century. 13 An intradermal injection of serum from an individual with solar urticaria can passively transfer the condition to a normal individual, 10 , 16 , 17 , 21 , 75 although this does not always occur. Heating the serum may destroy its capacity for passive transfer.…”

“…2 In 1923, Duke 3 suggested the name “solar urticaria” for this condition, and, in 1928, the urticarial response was quantified by phototesting with increasing doses of different wavelengths. 4–11 Action spectra were thus determined already in the early research using artificial light sources and different types of filter. 5–21 Although wavelengths between 300 and 800 nm and even longer 12–18 , 19 have been reported, the action spectrum for most patients is between 300 and 500 nm.…”

“…5–21 Although wavelengths between 300 and 800 nm and even longer 12–18 , 19 have been reported, the action spectrum for most patients is between 300 and 500 nm. In 1942, Rajka 10 reported that solar urticaria could be passively transferred to normal volunteers by an intradermal injection of serum from a person with solar urticaria. This was confirmed by other authors.…”

“…4 Action spectra were thus determined already in the early research using artificial light sources and different types of filter. [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] Although wavelengths between 300 and 800 nm and even longer 12,19 have been reported, the action spectrum for most patients is between 300 and 500 nm. In 1942, Rajka 10 reported that solar urticaria could be passively transferred to normal volunteers by an intradermal injection of serum from a person with solar urticaria.…”