Participation of bone marrow stromal precursor cells in bone regeneration in transosseous osteosynthesis

Hizarov, G. A.; Palienko, L. A.; Переслыцких, П. Ф.; Galanova, R. Ya.; Tolmacheva, Svetlana V.; Baldin, Yu. P.; Tret'yakova, I. P.

doi:10.1007/bf00830922

Cited by 2 publications

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“…Despite that bone lengthening attempts had been made before the era of Ilizarov [ 5 ], bone lengthening tactics and the phenomena that undergo during this procedure were another great achievement of Prof. Ilizarov and his school researchers. The basic idea of lengthening is reproduction of the natural growth provided by the conditions of distraction under the tension stress effect that induce bone cell differentiation, expansion and morphogenesis [ 46 ]. A special automated device was invented and patented (23.09.81) that is able to produce high-frequency distraction to bring bone lengthening closer to the natural bone growth.…”

Section: Ilizarov Methods In the Contemporary Orthopaedic Practicementioning

confidence: 99%

Contribution of G.A. Ilizarov to bone reconstruction: historical achievements and state of the art

Губин¹,

Borzunov²,

Марченкова³

et al. 2016

Strategies in Trauma and Limb Reconstruction

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Methodological solutions of Prof. G.A. Ilizarov are the core stone of the contemporary bone lengthening and reconstruction surgery. They have been acknowledged in the orthopaedic world as one of the greatest contributions to treating bone pathologies. The Ilizarov method of transosseous compression–distraction osteosynthesis has been widely used for managing bone non-union and defects, bone infection, congenital and posttraumatic limb length discrepancies, hand and foot disorders. The optimal conditions for implementing distraction and compression osteogenesis were proven by numerous experimental studies that Prof. G.A. Ilizarov organized and supervised at a large orthopaedic research institute in Kurgan. The tension stress effect on regeneration and growth of tissues was thoroughly investigated with radiographic, histological and biochemical methods. The impact of the Ilizarov method on the progress of bone lengthening and reconstruction surgery could be called revolutionary.

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Section: Ilizarov Methods In the Contemporary Orthopaedic Practicementioning

confidence: 99%

Contribution of G.A. Ilizarov to bone reconstruction: historical achievements and state of the art

Губин¹,

Borzunov²,

Марченкова³

et al. 2016

Strategies in Trauma and Limb Reconstruction

View full text Add to dashboard Cite

show abstract

Stimulation of Distraction Osteogenesis in Limb Lengthening: Our Concept

Шевцов

Leonchuk

2021

Traumatology and Orthopedics of Russia

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Background. Currently, limb lengthening is a widespread operation used in clinical and cosmetic practice. However, in the process of implementing this technology, its main drawbacks were revealed: the duration of treatment and the slowing down of the process of osteogenesis in the elongation zone. Rapid distraction in the external fixator or with an intramedullary rod can lead to a slowdown in osteogenesis and soft tissue complications, including neuropathy and soft tissue eruption.The aim — to develop a present its own concept of stimulating distraction osteogenesis in limb elongation, based on many years of clinical experience.Materials and Methods. This study is based on the long-term experience of the Ilizarov Center in limb lengthening (using data from clinical and experimental studies performed in the institution: more than 200 animals and 8000 patients), as well as literature data.Results. The introduction of the considered methods of stimulation of osteogenesis made it possible to significantly reduce the treatment time of patients and thereby reduce the number of possible complications characteristic of transosseous osteosynthesis. Systemic diseases, congenital malformation of the segment can negatively affect the quality of the new bone.Conclusions. The use of methods of stimulation of osteogenesis allows to reduce treatment time and increase osteogenesis when limb lengthening, which allows, if necessary, to provide re-lengthening of the segment without increasing treatment time.

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Participation of bone marrow stromal precursor cells in bone regeneration in transosseous osteosynthesis

Cited by 2 publications

References 1 publication

Contribution of G.A. Ilizarov to bone reconstruction: historical achievements and state of the art

Contribution of G.A. Ilizarov to bone reconstruction: historical achievements and state of the art

Stimulation of Distraction Osteogenesis in Limb Lengthening: Our Concept

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