“…A number of cases of ring 14 chromosome have also been reported [Amarose et al, 1980;Fryns et al, 1982;Gilgenkrantz et al, 1971;Jalbert et al, 1977;McBride and Oppenheimer, 1980;Schmidt et al, 1981;Sparkes et al, 1977;Vekemens et al, 19791. Regularly observed manifestations of ring 14 patients are microcephaly, moderate to severe psychomotor and growth retardation, dolichocephaly, high forehead, downward-slanting palpebral fissures, epicanthic folds, short neck, seizures, and neurological abnormalities including tremor, athetosis, hypotonia, and hypertonia.…”