Partial Spontaneous Bone Regeneration Subsequent to Mandibulectomy

Martins, Wilson; Ávila, Lúcia Fátima de Castro

doi:10.5005/jcdp-5-3-108

Cited by 12 publications

(7 citation statements)

References 13 publications

(16 reference statements)

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“…[ 3 , 4 , 18 ] The literature review in this study clarified that spontaneous regeneration of the mandible was usually observed in young and middle aged patients. [ 3 , 5 – 12 ] However, Okoturo et al suggested that increasing age might not imply a decrease in periosteal bone-regenerating potential, and the present case of this report supported that suggestion. [ 18 ] However, it is necessary to consider that the patient in this case had used bisphosphonates as treatment for bone metastasis from breast cancer.…”

Section: Discussionsupporting

confidence: 68%

“…Twenty four patients (15 males and 9 females) were included in this review (Table 1 ). [ 3 , 5 – 12 ] The youngest was 6 years’ old, and the oldest was 51 years’ old, and their mean age and standard deviation was 21.6 ± 12.9 years. [ 3 , 5 – 12 ] The most common disease associated with surgical procedures was ameloblastoma (12 patients).…”

Section: Resultsmentioning

confidence: 99%

“…[ 3 , 5 – 12 ] The youngest was 6 years’ old, and the oldest was 51 years’ old, and their mean age and standard deviation was 21.6 ± 12.9 years. [ 3 , 5 – 12 ] The most common disease associated with surgical procedures was ameloblastoma (12 patients). [ 3 , 5 – 12 ] There is no case of MRONJ in those reports.…”

Section: Resultsmentioning

confidence: 99%

“…[ 3 , 5 – 12 ] The most common disease associated with surgical procedures was ameloblastoma (12 patients). [ 3 , 5 – 12 ] There is no case of MRONJ in those reports. There were some cases performed immediate reconstruction, and some cases preserved the periosteum.…”

Section: Resultsmentioning

confidence: 99%

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Spontaneous regeneration of the mandible following hemimandibulectomy for medication-related osteonecrosis of the jaw

Matsuda

Yoshida²,

Shimada³

et al. 2020

Medicine

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Rationale: Medication-related osteonecrosis of the jaw decreases quality of life of patients with cancer. The debate about it continues regarding the risk factors, etiology, and treatment methods, and so on. Also, spontaneous regeneration of the mandible is clinically rare. Patient concerns: A 67-year-old woman presented to the authors’ department complaining of pain, swelling, and pus discharge from a fistula. She previously had breast cancer bone metastases and had received antiresorptive intravenous bisphosphonate. Diagnosis: The patient was diagnosed with medication-related osteonecrosis of the jaw. Interventions: She received conservative therapy with antibiotics and surgical therapy as sequestrectomy under general anesthesia; however, the lesion did not heal. Thirty months after the MRONJ diagnosis, when she was 70 years’ old, she underwent a left hemimandibulectomy without reconstruction under general anesthesia. Outcomes: Spontaneous regeneration of the mandible was observed by follow-up imaging examinations. The patient has no current subjective or objective symptoms. Lessons: This is the first case report of the spontaneous mandibular regeneration after surgery for medication-related osteonecrosis of the jaw. Additionally, this case was the oldest patient among the published mandibular regeneration cases.

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Section: Discussionsupporting

confidence: 68%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Spontaneous regeneration of the mandible following hemimandibulectomy for medication-related osteonecrosis of the jaw

Matsuda

Yoshida²,

Shimada³

et al. 2020

Medicine

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“…These have almost always been the answer for the more complex of dento-alveolar and even extra-oral defects Though dental implants have been successful means of rehabilitating patients with tooth loss, studies reported in the literature on the success of osseointegration of implants in regenerated bone have been relatively few and none of them have been done in the Indian scenario. [1][2][3] The ultimate test of regenerated bone is its amenability to function normally. 4 Studies that describe osseointegration of implants in bone which is regenerated in large volume bony defects as in cases of cysts and tumors are few.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Osseo Integrated Implants in Regenerated Jaw Bones after Cyst Enucleation

Burman¹

2013

IOSR-JDMS

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Aims & Objective: To evaluate if the implants can be osseointegrated in regenerated bone of patients who had large bony defects following odontogenic cyst enucleation. Material & Methods: A total of five patients were chosen for the study, implants were placed one year after surgical cyst enucleation The patients were assessed clinically and radiologically periodically i.e. every month , till 6 months after placement of implant. The success criteria included absence of any sign of periimplant inflammation , clinical mobility of the implant and abutment and finally absence of any peri implant radiolucency when seen on the radiograph. Results: A total of 15 implants were placed in five patients having regenerated bone with 93.3 % osseointegration. One patient showed failure i.e. implant mobility fifteen days after placement. The failure was attributed to poor quality of regenerated bone. Conclusion: By the findings of this study, we can safely conclude that implants can be successfully osseointegrated in regenerated bone , however poor quality of regenerated bone is the main cause of failure. However studies with larger sample size and concurrent HBO therapy to accelerate bone healing can be done in future.

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Self-Regeneration of the Mandible Following Hemimandibulectomy for Ameloblastoma: A Case Report and Review of Literature

Ahmad

Omami

2012

J. Maxillofac. Oral Surg.

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Resection of the mandible with immediate or delayed graft reconstruction is widely used in the treatment of ameloblastoma involving a large portion of the mandible. The purpose of reconstruction is mainly to restore the esthetic appearance and mandibular function of the patient. Spontaneous regeneration of the mandible after resection is rarely encountered. This article reports a rare case of spontaneous regeneration of the mandible after hemimandibulectomy for ameloblastoma in a 16-year-old male patient. We discuss the theories pertaining to the mechanism and source of the new bone formation in this case and review the English literature.

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Partial Spontaneous Bone Regeneration Subsequent to Mandibulectomy

Cited by 12 publications

References 13 publications

Spontaneous regeneration of the mandible following hemimandibulectomy for medication-related osteonecrosis of the jaw

Spontaneous regeneration of the mandible following hemimandibulectomy for medication-related osteonecrosis of the jaw

Evaluation of Osseo Integrated Implants in Regenerated Jaw Bones after Cyst Enucleation

Self-Regeneration of the Mandible Following Hemimandibulectomy for Ameloblastoma: A Case Report and Review of Literature

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